Palladium catalyzed chemo- and site-selective C-H acetoxylation and hydroxylation of oxobenzoxazine derivatives

被引：27

作者：

Bakthadoss, Manickam ^{[1
]}

Kumar, Polu Vijay ^{[1
]}

Kumar, Ravan ^{[1
]}

Agarwal, Vishal ^{[1
]}

机构：

[1] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 18期

关键词：

DIRECTING GROUP; ARENES; HALOGENATION; OXIDATION; AMINATION; ALCOHOLS; QUINAZOLINONES; SULFONYLATION; OXYGENATION; INHIBITORS;

D O I：

10.1039/c9ob00642g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient protocol for the introduction of acetoxy and hydroxy functionalities on unactivated aryl sp2 carbons of oxobenzoxazine derivatives via an ortho-C-H activation reaction using a palladium catalyst has been developed for the first time. Interestingly, this intermolecular C-H functionalization reaction takes place in a facile and simple manner with high chemo-and site selectivity.

引用

页码：4465 / 4469

页数：5

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