Atopy and asthma: genetic variants of IL-4 and IL-13 signalling

被引：235

作者：

Shirakawa, T ^{[1
]}

Deichmann, KA

Izuhara, K

Mao, XQ

Adra, CN

Hopkin, JM

机构：

[1] Univ Coll Swansea, Expt Med Unit, Swansea SA2 8PP, W Glam, Wales

[2] Univ Freiburg, Univ Childrens Hosp, Freiburg, Germany

[3] Kyushu Univ, Fac Med, Dept Clin Chem & Lab Med, Fukuoka 812, Japan

[4] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Med,Div Hematol Oncol, Boston, MA 02215 USA

[5] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Pathol,Div Hematol Oncol, Boston, MA 02215 USA

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 02期

关键词：

D O I：

10.1016/S0167-5699(99)01492-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent genetic and functional studies highlight the importance of IL-4/IL-13 signalling in the development of asthma and atopy. Here, Taro Shirakawa and colleagues discuss genetic variants of IL-4/IL-13 signalling, and whether they promote asthma or atopy among different ethnic groups.

引用

页码：60 / 64

页数：5

共 31 条

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