Effects of stocking density on growth performance, blood parameters and immunity of growing pigs

This study was conducted to evaluate the effects of different stocking densities on growth performance, blood parameters, intestinal morphology and intestinal immunity of growing pigs. A total of 288 male pigs (44.35 +/- 0.50 kg) were randomly assigned to groups with stocking densities of 2.46, 1.23 and 0.82 m(2)/pig for a month. The results showed that there was no significant difference on growth performance among groups. Pigs in the stocking density of 0.82 m(2)/pig had the lowest backfat thickness and spleen weight index among groups (P < 0.05). With increasing stocking density, the serum concentrations of blood urea nitrogen (BUN), transglutaminase (TGG), alkaline phosphatase (AKP) and immunoglobulin A (IgA) were increased, and albumin (ALB), albumin-to-globulin ratio (ALB:GLO), insulin-like growth factor-1 (IGF-1) and immunoglobulin (IgM) were decreased (P < 0.05), and cortisol tended to increase and glucose tended to decrease (0.05 < P < 0.1). Compared with the stocking density of 2.46 m(2)/pig, the ileal villus height and jejuna[ villus width decreased in stocking densities of 1.23 and 0.82 m(2)/pig (P < 0.05). The duodenal villus height and ileal villus width in the stocking density of 0.82 m(2)/pig were the lowest among 3 groups (P < 0.05). The content of immunoglobulin A in duodenum, jejunum and ileum mucosa increased along with increasing density (P < 0.05). The contents of interleukin (IL)-2 in the spleen or liver and IL-10 in the spleen were higher in the stocking density of 0.82 m(2)/pig than in other 2 groups. These results showed that stocking density could affect the metabolism, intestinal morphology, and immunity of growing pigs and 1.23 m(2)/pig may be the suitable stocking density for the growing pigs in the present study. (C) 2020, Chinese Association of Animal Science and Veterinary Medicine. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.