Molecular epidemiology of Clostridium difficile for clinical practice

被引:2
作者
Tschudin-Sutter, Sarah [1 ]
机构
[1] Univ Basel Hosp, Div Infect Dis & Hosp Epidemiol, CH-4031 Basel, Switzerland
关键词
Clostridium difficile; PCR-ribotype; 027; PCR-ribotype-078; molecular epidemiology; RIBOTYPE; 027; INCREASED SPORULATION; BINARY TOXIN; INFECTION; DISEASE; EMERGENCE; DIARRHEA; COMMUNITY; STRAIN; MORTALITY;
D O I
10.4414/smw.2014.13995
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
During the last decade, the world has witnessed numerous outbreaks of Clostridium difficile infections (CDI) in healthcare settings. Increasing incidence rates of CDI have been mainly attributed to the successful global spread of a more virulent strain of C. difficile - namely PCR-ribotype 027. More recent studies, however, point to the emergence of other ribotypes as the main cause of the continuing epidemic. This review summarises the current literature on the molecular epidemiology of C. difficile as well as its implications for clinical practice.
引用
收藏
页数:6
相关论文
共 67 条
  • [11] Bishara J, 2011, ISR MED ASSOC J, V13, P338
  • [12] Clostridium difficile O27 colitis: Hospital-onset but community-acquired
    Buffet-Bataillon, S.
    Tattevin, P.
    Senechal, H.
    Cormier, M.
    Vincent, P.
    [J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2012, 31 (09) : 2263 - 2267
  • [13] Centers for Disease Control and Prevention (CDC), 2005, MMWR Morb Mortal Wkly Rep, V54, P1201
  • [14] Clostridium difficile ribotype 027 arrives in Hong Kong
    Cheng, Vincent C. C.
    Yam, W. C.
    Chan, Jasper F. W.
    To, Kelvin K. W.
    Ho, P. L.
    Yuen, K. Y.
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2009, 34 (05) : 492 - 493
  • [15] Epidemiology of Community-Associated Clostridium difficile Infection, 2009 Through 2011
    Chitnis, Amit S.
    Holzbauer, Stacy M.
    Belflower, Ruth M.
    Winston, Lisa G.
    Bamberg, Wendy M.
    Lyons, Carol
    Farley, Monica M.
    Dumyati, Ghinwa K.
    Wilson, Lucy E.
    Beldavs, Zintars G.
    Dunn, John R.
    Gould, L. Hannah
    MacCannell, Duncan R.
    Gerding, Dale N.
    McDonald, L. Clifford
    Lessa, Fernanda C.
    [J]. JAMA INTERNAL MEDICINE, 2013, 173 (14) : 1359 - 1367
  • [16] Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread
    Clements, Archie C. A.
    Magalhaes, Ricardo J. Soares
    Tatem, Andrew J.
    Paterson, David L.
    Riley, Thomas V.
    [J]. LANCET INFECTIOUS DISEASES, 2010, 10 (06) : 395 - 404
  • [17] Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
    Cohen, Stuart H.
    Gerding, Dale N.
    Johnson, Stuart
    Kelly, Ciaran P.
    Loo, Vivian G.
    McDonald, L. Clifford
    Pepin, Jacques
    Wilcox, Mark H.
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2010, 31 (05) : 431 - 455
  • [18] Coignard B, 2006, EUROSURVEILLANCE, V11, DOI 10.2807/esw.11.37.03044-en
  • [19] European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection
    Debast, S. B.
    Bauer, M. P.
    Kuijper, E. J.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2014, 20 : 1 - 26
  • [20] C-difficile may have killed 2000 in Quebec:: study
    Eggertson, L
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2005, 173 (09) : 1020 - 1021