Rapid surface plasmon resonance immunoassays for the determination of mycotoxins in cereals and cereal-based food products

In recent times surface plasmon resonance has demonstrated its applicability to the detection of a wide range of contaminants in food and feed including mycotoxins in cereals and cereal-based food products. Commercially available, laboratory-based systems have exploited high affinity polyclonal, monoclonal and recombinant antibodies and robust sensing surfaces to provide rapid, accurate and sensitive means of determining these toxins. In addition many custom-built, prototype devices have shown a great deal of potential for this particular application and have included the combination of surface plasmon resonance with enzyme-derivatised sensors, molecularly imprinted polymers, fluorescence spectroscopy and the use of gold nanoparticles for signal enhancement. Of note is the lack of available devices that allow the detection of multiple mycotoxins simultaneously and portable devices that could be used in the field, therefore future research and development should focus on these areas to deliver cost-effective miniaturised devices with multiplexing capabilities.