Interplay between plasmid partition and postsegregational killing systems

被引:15
作者
Brendler, T [1 ]
Reaves, L [1 ]
Austin, S [1 ]
机构
[1] GRCBL, NCI Frederick, NCI, Ft Detrick, MD 21702 USA
关键词
D O I
10.1128/JB.186.8.2504-2507.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Active partition systems and postsegregational killing (PSK) systems are present together in naturally occurring low-copy-number plasmids. Theory suggests that PSK may act as the ultimate determinant of plasmid retention, whereas the partition system may minimize the growth penalty to the host, resulting in a near-ideal symbiosis when the systems combine. Here, we prove the validity of this principle for a specific case involving the P1par system and the mvp PSK system.
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页码:2504 / 2507
页数:4
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