A comparison between plasmapheresis and intravenous immunoglobulin in children with Guillain-Barre syndrome in Upper Egypt

被引:14
作者
Saad, Khaled [1 ]
Mohamad, Ismail L. [2 ]
Abd El-Hamed, Mohamed A. [3 ]
Tawfeek, Mostafa S. K. [2 ]
Ahmed, Ahmed E. [4 ]
Baseer, Khaled A. Abdel [4 ]
El-Shemy, Ahmed S. [5 ]
El-Houfey, Amira A. [6 ]
Tamer, Diaa M. [2 ]
机构
[1] Univ Assiut, Fac Med, Pediat, Assiut 71516, Egypt
[2] Assiut Univ, Fac Med, Dept Pediat, Assiut, Egypt
[3] Assiut Univ, Fac Med, Dept Neurol, Assiut, Egypt
[4] South Valley Univ, Qena Fac Med, Dept Pediat, Qena, Egypt
[5] Al Azhar Univ, Fac Med, Dept Pediat, Assiut, Egypt
[6] Assiut Univ, Dept Community Hlth Nursing, Assiut, Egypt
关键词
children; Guillain-Barre Syndrome; intravenous immunoglobulin; plasmapheresis; outcome; CAMPYLOBACTER-JEJUNI; CHINESE CHILDREN; PLASMA-EXCHANGE; INFECTION;
D O I
10.1177/1756285615610471
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: The aim of our study is to assess the clinico-electrophysiological profile of children with Guillain-Barre syndrome (GBS) in Upper Egypt and to compare the efficacy of plasmapheresis versus other treatment modalities. Patients and methods: This was a retrospective study of children from January 2010 to October 2014 diagnosed as GBS. It included 62 cases. Results: Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) was the most prevalent type of GBS in our locality. As regards the treatment, 32 cases received plasmapheresis while 30 patients received intravenous immunoglobulin. We found a significant decrease in the duration of hospitalization and a significant increase in the number of children with complete recovery in cases treated with plasmapheresis. Conclusion: GBS is not uncommon in children of Upper Egypt, with AIDP the most prevalent type. Plasmapheresis is the best treatment modalities for GBS as it reduces the duration of hospital stay and hastens the recovery of those children.
引用
收藏
页码:3 / 8
页数:6
相关论文
共 29 条
[1]   Management of children with Guillain-Barre syndrome [J].
Agrawal, S. ;
Peake, D. ;
Whitehouse, W. P. .
ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION, 2007, 92 (06) :161-168
[2]   ASSESSMENT OF CURRENT DIAGNOSTIC-CRITERIA FOR GUILLAIN-BARRE-SYNDROME [J].
ASBURY, AK ;
CORNBLATH, DR .
ANNALS OF NEUROLOGY, 1990, 27 :S21-S24
[3]  
Chieng SK, 2007, J PEDIATR NEUROL, V5, P153
[4]   Guillain-Barre syndrome -: A prospective, population-based incidence and outcome survey [J].
Chiò, A ;
Cocito, D ;
Leone, M ;
Giordana, MT ;
Mora, G ;
Mutani, R .
NEUROLOGY, 2003, 60 (07) :1146-1150
[5]   A preliminary, randomized, multicenter study comparing intravenous immunoglobulin, plasma exchange, and immune adsorption in Guillain-Barre syndrome [J].
Diener, HC ;
Haupt, WF ;
Kloss, TM ;
Rosenow, F ;
Philipp, T ;
Koeppen, S ;
Vietorisz, A .
EUROPEAN NEUROLOGY, 2001, 46 (02) :107-109
[6]  
Gorthi SP, 2006, NATL MED J INDIA, V19, P137
[7]   Reactivity of serum IgG anti-GM1 ganglioside antibodies with the lipopolysaccharide fractions of Campylobacter jejuni isolates from patients with Guillain-Barre syndrome (GBS) [J].
Gregson, NA ;
Rees, JH ;
Hughes, RAC .
JOURNAL OF NEUROIMMUNOLOGY, 1997, 73 (1-2) :28-36
[8]   GUILLAIN-BARRE-SYNDROME IN NORTHERN CHINA - RELATIONSHIP TO CAMPYLOBACTER-JEJUNI INFECTION AND ANTI-GLYCOLIPID ANTIBODIES [J].
HO, TW ;
MISHU, B ;
LI, CY ;
GAO, CY ;
CORNBLATH, DR ;
GRIFFIN, JW ;
ASBURY, AK ;
BLASER, MJ ;
MCKHANN, GM .
BRAIN, 1995, 118 :597-605
[9]   Practice parameter: Immunotherapy for Guillain-Barre syndrome - Report of the quality standards subcommittee of the American Academy of Neurology [J].
Hughes, RAC ;
Wijdicks, EFM ;
Barohn, R ;
Benson, E ;
Cornblath, DR ;
Hahn, AF ;
Meythaler, JM ;
Miller, RG ;
Sladky, JT ;
Stevens, JC .
NEUROLOGY, 2003, 61 (06) :736-740
[10]  
HUGHES RAC, 1995, REV NEUROL, V151, P291