Public attitudes in Japan towards human-animal chimeric embryo research using human induced pluripotent stem cells

被引:15
作者
Sawai, Tsutomu [1 ]
Hatta, Taichi [1 ]
Fujita, Misao [1 ]
机构
[1] Kyoto Univ, Uehiro Res Div iPS Cell Eth, Ctr iPS Cell Res & Applicat, Sakyo Ku, 53 Kawahara Cho, Kyoto 6068507, Japan
关键词
human-animal chimeras; human-animal chimeric embryos; human-induced pluripotent stem cells; Japan; public attitudes; questionnaire survey; HUMAN-NONHUMAN CHIMERAS; CROSSING SPECIES BOUNDARIES; HUMAN-DIGNITY; HUMAN ORGANS; ETHICAL-ISSUES; MORAL STATUS; SCIENCE; XENOTRANSPLANTATION; TRANSPLANTATION; SPAIN;
D O I
10.2217/rme-2016-0171
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Aim: To understand the steps and objectives for which Japanese people are willing to accept human-animal chimeric embryo research using human induced pluripotent stem cells. Methods: An internet-based survey was conducted for the general public and researchers in Japan in 2016. Results: Over 60% of the public and 83.8% of researchers supported the creation of human-swine chimeras and 81.0% of the public and 92.4% of researchers supported the creation of human-swine chimeric embryos. Discussion: When presented with a graded view of human-swine chimeric embryo research with concomitant, specific objectives, a large majority of the general public as well as researchers are willing to accept this research with the aims of disease study, novel drug and treatment development, and transplantation.
引用
收藏
页码:233 / 248
页数:16
相关论文
共 76 条
[61]   The moral insignificance of crossing species boundaries [J].
Siegel, AW .
AMERICAN JOURNAL OF BIOETHICS, 2003, 3 (03) :33-34
[62]   The influence of trust and perceptions of risks and benefits on the acceptance of gene technology [J].
Siegrist, M .
RISK ANALYSIS, 2000, 20 (02) :195-203
[63]   Perception of hazards: The role of social trust and knowledge [J].
Siegrist, M ;
Cvetkovich, G .
RISK ANALYSIS, 2000, 20 (05) :713-719
[64]   Attitude toward xenotransplantation of patients prior and after human organ transplantation [J].
Stadlbauer, V. ;
Stiegler, P. ;
Mueller, S. ;
Schweiger, M. ;
Sereinigg, M. ;
Tscheliessnigg, K. H. ;
Freidl, W. .
CLINICAL TRANSPLANTATION, 2011, 25 (03) :495-503
[65]   At the edge of humanity: Human stem cells, chimeras, and moral status [J].
Streiffer, R .
KENNEDY INSTITUTE OF ETHICS JOURNAL, 2005, 15 (04) :347-370
[66]  
Streiffer R., 2014, STANFORD ENCY PHILOS
[67]   Free the animals? Investigating attitudes toward animal testing in Britain and the United States [J].
Swami, Viren ;
Furnham, Adrian ;
Christopher, Andrew N. .
SCANDINAVIAN JOURNAL OF PSYCHOLOGY, 2008, 49 (03) :269-276
[68]  
The Chimeric Embryo (HACE) Ministry of Education 24 Culture Sports Science and Technology, 2016, REP INV DISC TREATM
[69]  
The Home Office, 2013, OP REG HANDL RES INV
[70]  
The Home office, 2016, GUID US HUM MAT AN