Evaluation of Coronary Plaques and Stents with Conventional and Photon-counting CT: Benefits of High-Resolution Photon-counting CT

被引：52

作者：

Rajagopal, Jayasai R. ^{[1
]}

Farhadi, Faraz ^{[2
]}

Richards, Taylor ^{[1
]}

Nikpanah, Moozhan ^{[2
]}

Sahbaee, Pooyan ^{[5
]}

Shanbhag, Sujata M. ^{[3
]}

Bandettini, W. Patricia ^{[3
]}

Saboury, Babak ^{[2
]}

Malayeri, Ashkan A. ^{[2
]}

Pritchard, William F. ^{[4
]}

Jones, Elizabeth C. ^{[2
]}

Samei, Ehsan ^{[1
]}

Chen, Marcus Y. ^{[3
]}

机构：

[1] Duke Univ, Dept Radiol, Med Phys Grad Program, Med Ctr,Carl E Ravin Adv Imaging Labs, Durham, NC USA

[2] NHLBI, Dept Radiol & Imaging Sci, Clin Ctr, 10 Ctr Dr,Bldg 10,Room B1D417, Bethesda, MD 20892 USA

[3] NHLBI, Cardiovasc Branch, 10 Ctr Dr,Bldg 10,Room B1D417, Bethesda, MD 20892 USA

[4] NIH, Ctr Intervent Oncol Radiol & Imaging Sci, Clin Ctr, 10 Ctr Dr,Bldg 10,Room B1D417, Bethesda, MD 20892 USA

[5] Siemens Med Solut USA, Malvern, PA USA

来源：

RADIOLOGY-CARDIOTHORACIC IMAGING | 2021年 / 3卷 / 05期

基金：

美国国家卫生研究院;

关键词：

CT-Spectral Imaging (Dual Energy); Phantom Studies; Cardiac; Physics; Technology Assessment; COMPUTED-TOMOGRAPHY; ANGIOGRAPHY;

D O I：

10.1148/ryct.2021210102

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: To compare the performance of energy-integrating detector (EID) CT, photon-counting detector CT (PCCT), and high -resolution PCCT (HR-PCCT) for the visualization of coronary plaques and reduction of stent artifacts in a phantom model. Materials and Methods: An investigational scanner with EID and PCCT subsystems was used to image a coronary artery phantom con-taining cylindrical probes simulating different plaque compositions. The phantom was imaged with and without coronary stents using both subsystems. Images were reconstructed with a clinical cardiac kernel and an additional HR-PCCT kernel. Regions of interest were drawn around probes and evaluated for in-plane diameter and a qualitative comparison by expert readers. A linear mixed-effects model was used to compare the diameter results, and a Shrout-Fleiss intraclass correlation coefficient was used to assess consistency in the reader study. Results: Comparing in-plane diameter to the physical dimension for nonstented and stented phantoms, measurements of the HR-PCCT images were more accurate (nonstented: 4.4% +/- 1.1 [standard deviation], stented: -9.4% +/- 4.6) than EID (nonstented: 15.5% +/- 4.0, stented: -19.5% +/- 5.8) and PCCT (nonstented: 19.4% +/- 2.5, stented: -18.3% +/- 4.4). Our analysis of variance found diameter measurements to be different across image groups for both nonstented and stented cases (P < .001). HR-PCCT showed less change on average in percent stenosis due to the addition of a stent (-5.5%) than either EID (+90.5%) or PCCT (+313%). For both nonstented and stented phantoms, observers rated the HR-PCCT images as having higher plaque conspicuity and as being the image type that was least impacted by stent artifacts, with a high level of agreement (interclass correlation coefficient = 0.85). Conclusion: Despite increased noise, HR-PCCT images were able to better visualize coronary plaques and reduce stent artifacts com-pared with EID or PCCT reconstructions. (C) RSNA, 2021

引用

页数：8

共 23 条

[11] Coronary CT angiography and high-risk plaque morphology [J].

Motoyama S. ;

Sarai M. ;

Narula J. ;

Ozaki Y. .

Cardiovascular Intervention and Therapeutics, 2013, 28 (1) :1-8

[12] Computed Tomographic Angiography Characteristics of Atherosclerotic Plaques Subsequently Resulting in Acute Coronary Syndrome [J].

Motoyama, Sadako ;

Sarai, Masayoshi ;

Harigaya, Hiroto ;

Anno, Hirofumi ;

Inoue, Kaori ;

Hara, Tomonori ;

Naruse, Hiroyuki ;

Ishii, Junichi ;

Hishida, Hitoshi ;

Wong, Nathan D. ;

Virmani, Renu ;

Kondo, Takeshi ;

Ozaki, Yukio ;

Narula, Jagat .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (01) :49-57

[13]

Nikolaou K, 2011, INSIGHTS IMAGING, V2, P9, DOI 10.1007/s13244-010-0049-0

[14] Variability of stenosis characterization: Impact of coronary vessel motion in cardiac CT [J].

Richards, Taylor ;

Segars, Paul ;

Samei, Ehsan .

MEDICAL IMAGING 2018: PHYSICS OF MEDICAL IMAGING, 2018, 10573

[15] Quantification of uncertainty in the assessment of coronary plaque in CCTA through a dynamic cardiac phantom and 3D-printed plaque model [J].

Richards, Taylor ;

Sturgeon, Gregory M. ;

Ramirez-Giraldo, Juan Carlos ;

Rubin, Geoffrey D. ;

Koweek, Lynne Hurwitz ;

Segars, William Paul ;

Samei, Ehsan .

JOURNAL OF MEDICAL IMAGING, 2018, 5 (01)

[16] INTRACLASS CORRELATIONS - USES IN ASSESSING RATER RELIABILITY [J].

SHROUT, PE ;

FLEISS, JL .

PSYCHOLOGICAL BULLETIN, 1979, 86 (02) :420-428

[17] Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging [J].

Sigovan, Monica ;

Si-Mohamed, Salim ;

Bar-Ness, Daniel ;

Mitchell, Julia ;

Langlois, Jean-Baptiste ;

Coulon, Philippe ;

Roessl, Ewald ;

Blevis, Ira ;

Rokni, Michal ;

Rioufol, Gilles ;

Douek, Philippe ;

Boussel, Loic .

SCIENTIFIC REPORTS, 2019, 9 (1)

[18] Quarter-millimeter spectral coronary stent imaging with photon-counting CT: Initial experience [J].

Symons, Rolf ;

De Bruecker, Yves ;

Roosen, John ;

Van Camp, Laurent ;

Cork, Tyler E. ;

Kappler, Steffen ;

Ulzheimer, Stefan ;

Sandfort, Veit ;

Bluemke, David A. ;

Pourmorteza, Amir .

JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, 2018, 12 (06) :509-515

[19] Photon Counting Computed Tomography With Dedicated Sharp Convolution Kernels Tapping the Potential of a New Technology for Stent Imaging [J].

von Spiczak, Jochen ;

Mannil, Manoj ;

Peters, Benjamin ;

Hickethier, Tilman ;

Baer, Matthias ;

Henning, Andre ;

Schmidt, Bernhard ;

Flohr, Thomas ;

Manka, Robert ;

Maintz, David ;

Alkadhi, Hatem .

INVESTIGATIVE RADIOLOGY, 2018, 53 (08) :486-494

[20] Photon-counting CT: Technical Principles and Clinical Prospects [J].

Willemink, Martin J. ;

Persson, Mats ;

Pourmorteza, Amir ;

Pelc, Norbert. ;

Fleischmann, Dominik .

RADIOLOGY, 2018, 289 (02) :293-312

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