Nipah Virus Infection

被引：181

作者：

Ang, Brenda S. P. ^{[1
,2
,3
]}

Lim, Tchoyoson C. C. ^{[4
,5
]}

Wang, Linfa ^{[6
,7
]}

机构：

[1] Tan Tock Seng Hosp, Dept Infect Dis, Singapore, Singapore

[2] Lee Kong Chian Sch Med, Singapore, Singapore

[3] Natl Univ Singapore, Singapore, Singapore

[4] Natl Neurosci Inst, Dept Neuroradiol, Singapore, Singapore

[5] Duke NUS Med Sch, Singapore, Singapore

[6] Duke NUS Med Sch, Programme Emerging Infect Dis, Singapore, Singapore

[7] Duke Univ, Duke Global Hlth Inst, Durham, NC USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2018年 / 56卷 / 06期

关键词：

Nipah; encephalitis; outbreaks; DATE PALM SAP; ENCEPHALITIS OUTBREAK; CLINICAL-FEATURES; ABATTOIR WORKERS; HENDRA VIRUS; PIG-FARMERS; TRANSMISSION; BANGLADESH; MALAYSIA; BATS;

D O I：

10.1128/JCM.01875-17

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.

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