Progenitor and stem cells for bone and cartilage regeneration

被引：58
作者：
El Tamer, M. K. [1 ,2 ]
Reis, R. L. [1 ,2 ]
机构：
[1] Univ Minho, Res Grp 3Bs, European Inst Excellence Tissue Engn & Regenerat, P-4806909 Taipas, Guimaraes, Portugal
[2] IBB, PT Govt Associated Lab, Guimaraes, Portugal
来源：
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE | 2009年 / 3卷 / 05期
关键词：
stem cells; stem cell sources; progenitor cells; regeneration; bone; osteogenesis; cartilage; chondrogenesis; tissue engineering; compromised tissue replacement; functional tissue repair; regenerative medicine; MARROW STROMAL CELLS; HUMAN ADIPOSE-TISSUE; IN-VITRO DIFFERENTIATION; CRITICAL-SIZE DEFECTS; UMBILICAL-CORD BLOOD; VIVO GENE-THERAPY; CHONDROGENIC DIFFERENTIATION; OSTEOGENIC DIFFERENTIATION; ARTICULAR-CARTILAGE; POTENTIAL SOURCE;
D O I：
10.1002/term.173
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Research in regenerative medicine is developing at a significantly quick pace. Cell-based bone and cartilage replacement is an evolving therapy aiming at the treatment of patients who suffer from limb amputation, damaged tissues and various bone and cartilage-related disorders. Stem cells are undifferentiated cells with the capability to regenerate into one or more committed cell lineages. Stem cells isolated from multiple sources have been finding widespread use to advance the field of tissue repair. The present review gives a comprehensive over-view of the developments in stem cells originating from different tissues and suggests future prospects for functional bone and cartilage tissue regeneration. Copyright (C) 2009 John Wiley & Sons, Ltd.
引用
收藏
页码：327 / 337
页数：11
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