Structure of the avian mitochondrial cytochrome bc1 complex

被引:35
作者
Berry, EA [1 ]
Huang, LS
Zhang, ZL
Kim, SH
机构
[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Dept Chem, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Lawrence Berkeley Lab, Grad Grp Phys, Berkeley, CA 94720 USA
关键词
ubiquinol : cytochrome c oxidoreductase; membrane protein; electron transfer; structure determination;
D O I
10.1023/A:1005459426843
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
There are now four structures of vertebrate mitochondrial bc(1) complexes available in the protein databases and structures from yeast and bacterial sources are expected soon. This review summarizes the new information with emphasis on the avian cytochrome bc(1) complex (PDB entries 1BCC and 3BCC). The Rieske iron-sulfur protein is mobile and this has been proposed to be important for catalysis. The binding sites for quinone have been located based on structures containing inhibitors and, in the case of the quinone reduction site Qi, the quinone itself.
引用
收藏
页码:177 / 190
页数:14
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