2-(anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands

被引：3
作者：
Prisinzano, T
Dukat, M
Law, H
Slassi, A
MacLean, N
DeLannoy, I
Glennon, RA
机构：
[1] Virginia Commonwealth Univ, Sch Pharm, Dept Med Chem, Richmond, VA 23298 USA
[2] NPS Pharmaceut, Mississauga, ON L4V 1V7, Canada
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2004年 / 14卷 / 18期
关键词：
serotonin migraine;
D O I：
10.1016/j.bmcl.2004.06.085
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
2-(Anilino)imidazolines were identified as novel human 5-HT1D receptor ligands, but offered no particular advantage over previously reported 2-(benzyl)imidazolines. Pharmacokinetic and functional data were obtained for selected 2-(benzyl)imidazoline derivatives. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4697 / 4699
页数：3
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