Clopidogrel in ST-elevation myocardial infarction

被引：5
|
作者：
Sabatine, Marc S.
机构：
[1] Brigham & Womens Hosp, Dept Med, Div Cardiovasc, Thrombolysis Myocardial Infarct TIMI Study Grp, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
来源：
EUROPEAN HEART JOURNAL SUPPLEMENTS | 2006年 / 8卷 / 0G期
关键词：
clopidogrel; fibrinolysis; ST-elevation myocardial infarction;
D O I：
10.1093/eurheartj/sul052
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Platelet adhesion, activation, and aggregation are central to the pathophysiology of the acute coronary syndromes (ACS). Clopidogrel, an oral thienopyridine derivative, is a platelet adenosine diphosphate (ADP)-receptor antagonist capable of inhibiting platelet activation. The benefits of clopidogrel in patients with stable coronary artery disease undergoing elective percutaneous coronary interventions (PCI) and in patients presenting with non-ST-elevation ACS are well established. This article will review the results of recent clinical trials in which the utility of clopidogrel in patients with ST-elevation myocardial infarction was evaluated.
引用
收藏
页码：G31 / G34
页数：4
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