Clopidogrel in ST-elevation myocardial infarction

被引：5

作者：

Sabatine, Marc S.

机构：

[1] Brigham & Womens Hosp, Dept Med, Div Cardiovasc, Thrombolysis Myocardial Infarct TIMI Study Grp, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

EUROPEAN HEART JOURNAL SUPPLEMENTS | 2006年 / 8卷 / 0G期

关键词：

clopidogrel; fibrinolysis; ST-elevation myocardial infarction;

D O I：

10.1093/eurheartj/sul052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Platelet adhesion, activation, and aggregation are central to the pathophysiology of the acute coronary syndromes (ACS). Clopidogrel, an oral thienopyridine derivative, is a platelet adenosine diphosphate (ADP)-receptor antagonist capable of inhibiting platelet activation. The benefits of clopidogrel in patients with stable coronary artery disease undergoing elective percutaneous coronary interventions (PCI) and in patients presenting with non-ST-elevation ACS are well established. This article will review the results of recent clinical trials in which the utility of clopidogrel in patients with ST-elevation myocardial infarction was evaluated.

引用

页码：G31 / G34

页数：4

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