Luteophanol D, new polyhydroxyl metabolite from marine dinoflagellate Amphidinium sp.

被引：42
作者：
Kubota, Takaaki [1 ]
Takahashi, Ayako [1 ]
Tsuda, Masashi [1 ]
Kobayashi, Jun'ichi [1 ]
机构：
[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan
来源：
MARINE DRUGS | 2005年 / 3卷 / 04期
关键词：
dinoflagellate; Amphidinium sp; luteophanol D; polyhydroxyl metabolite;
D O I：
10.3390/md304113
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Luteophanol D ( 1), a new polyhydroxyl linear carbon-chain metabolite, has been isolated from the cultured marine dinoflagellate Amphidinium sp., which was isolated from Okinawan marine acoel flatworm Pseudaphanostoma luteocoloris. The structure of 1 was elucidated by detailed analyses of 2D NMR spectra. Luteophanol D ( 1) possesses two tetrahydropyran rings and twenty-three hydroxyl groups on C-63-linear aliphatic chain with one exo-methylene and two methyl branches.
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页码：113 / 118
页数：6
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