Background: Among 10 provinces in Canada, Quebec has the second highest incidence of Crohn's disease (CD), based on data collected more than a decade ago. To date, there are no reports on the occurrence of ulcerative colitis (UC) and no updates on the occurrence of CD in Quebec. We sought to describe trends in the annual incidence and prevalence of inflammatory bowel disease in Quebec during 2001 to 2008. Methods: A population-based retrospective cohort study was conducted using the administrative health databases of Quebec. IBD cases were identified using a validated case definition requiring at least 1 hospitalization or 4 physician claims within a 2-year period. Incident cases were defined as individuals who had been free of inflammatory bowel disease for at least 2 years before the 2-year time span of the case definition. Results: We identified 24,377 CD and 15,346 UC cases. The mean age at diagnosis was 39 and 46 years for CD and UC, respectively. There was a significant decline in the annual incidence from 2001 to 2008 for both CD (P < 0.003) and UC (P < 0.001). No significant change with time was found in pediatric cases. The point prevalence in 2008 was 277 CD and 164 UC cases per 100,000 population. The average incidence was 17.4 CD cases per 100,000 person-years and 10.1 UC cases per 100,000 person-years. There was no predominance of urban or rural cases for either CD or UC. Conclusions: During 2001 to 2008, annual incidence for both CD and UC declined in Quebec. There was no significant change with time in incidence for pediatric cases.
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Herrinton, Lisa J.
;
Liu, Liyan
论文数: 0引用数: 0
h-index: 0
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Liu, Liyan
;
Lewis, James D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Lewis, James D.
;
Griffin, Patricia M.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Enter Dis Epidemiol Branch, Div Foodborne Bacterial & Mycot Dis, Natl Ctr Zoonot Vector Borne & Enter Dis, Atlanta, GA USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Griffin, Patricia M.
;
Allison, James
论文数: 0引用数: 0
h-index: 0
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Univ Calif San Francisco, Dept Internal Med, Div Gastroenterol, San Francisco, CA 94143 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Hou, Jason K.
;
Kramer, Jennifer R.
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Kramer, Jennifer R.
;
Richardson, Peter
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Richardson, Peter
;
Mei, Minghua
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Mei, Minghua
;
El-Serag, Hashem B.
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
机构:
Tampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Seinajoki Cent Hosp, Seinajoki, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Jussila, Airi
;
Virta, Lauri J.
论文数: 0引用数: 0
h-index: 0
机构:
Social Insurance Inst, Res Dept, Turku, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Virta, Lauri J.
;
Kautiainen, Hannu
论文数: 0引用数: 0
h-index: 0
机构:
Cent Finland Cent Hosp, Unit Family Practice, Jyvaskyla, Finland
Kuopio Univ Hosp, Unit Primary Hlth Care, Kuopio, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Kautiainen, Hannu
;
Rekiaro, Matti
论文数: 0引用数: 0
h-index: 0
机构:
Insurance Reg Western Finland, Social Insurance Inst, Seinajoki, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
机构:
Univ N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Kappelman, Michael D.
;
Moore, Kristen R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27599 USA
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Moore, Kristen R.
;
Allen, Jeffery K.
论文数: 0引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Allen, Jeffery K.
;
Cook, Suzanne F.
论文数: 0引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Herrinton, Lisa J.
;
Liu, Liyan
论文数: 0引用数: 0
h-index: 0
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Liu, Liyan
;
Lewis, James D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Lewis, James D.
;
Griffin, Patricia M.
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Dis Control & Prevent, Enter Dis Epidemiol Branch, Div Foodborne Bacterial & Mycot Dis, Natl Ctr Zoonot Vector Borne & Enter Dis, Atlanta, GA USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Griffin, Patricia M.
;
Allison, James
论文数: 0引用数: 0
h-index: 0
机构:
Kaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
Univ Calif San Francisco, Dept Internal Med, Div Gastroenterol, San Francisco, CA 94143 USAKaiser Permanente No Calif, Div Res, Oakland, CA 94612 USA
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Hou, Jason K.
;
Kramer, Jennifer R.
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Kramer, Jennifer R.
;
Richardson, Peter
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Richardson, Peter
;
Mei, Minghua
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Mei, Minghua
;
El-Serag, Hashem B.
论文数: 0引用数: 0
h-index: 0
机构:
Michael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
Baylor Coll Med, Dept Med, Houston, TX 77030 USAMichael E DeBakey VA Med Ctr, Houston VA HSR&D Ctr Excellence, Houston, TX USA
机构:
Tampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Seinajoki Cent Hosp, Seinajoki, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Jussila, Airi
;
Virta, Lauri J.
论文数: 0引用数: 0
h-index: 0
机构:
Social Insurance Inst, Res Dept, Turku, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Virta, Lauri J.
;
Kautiainen, Hannu
论文数: 0引用数: 0
h-index: 0
机构:
Cent Finland Cent Hosp, Unit Family Practice, Jyvaskyla, Finland
Kuopio Univ Hosp, Unit Primary Hlth Care, Kuopio, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
Kautiainen, Hannu
;
Rekiaro, Matti
论文数: 0引用数: 0
h-index: 0
机构:
Insurance Reg Western Finland, Social Insurance Inst, Seinajoki, FinlandTampere Univ Hosp, Dept Gastroenterol & Alimentary Tract Surg, Tampere, Finland
机构:
Univ N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Kappelman, Michael D.
;
Moore, Kristen R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27599 USA
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Moore, Kristen R.
;
Allen, Jeffery K.
论文数: 0引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA
Allen, Jeffery K.
;
Cook, Suzanne F.
论文数: 0引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Worldwide Epidemiol Dept, Chapel Hill, NC USAUniv N Carolina, Dept Pediat, Div Pediat Gastroenterol, Chapel Hill, NC 27599 USA