A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

被引：109

作者：

Tan, Li ^{[1
]}

Lin, Weiying ^{[1
]}

Zhu, Sasa ^{[1
]}

Yuan, Lin ^{[1
]}

Zheng, Kaibo ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 26期

关键词：

CAPILLARY ELECTROPHORETIC DETERMINATION; SELECTIVE DETECTION; SO2; SENSITIVITY; HYDRAZINE; SENSOR;

D O I：

10.1039/c4ob00132j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Based on a novel coumarin-quinolinium platform, probe 2 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for sulfite anions. The probe exhibited a wide dynamic concentration range for sulfite anions in a PBS buffer (containing 1 mg mL(-1) BSA). More importantly, the probe was suitable for ratiometric fluorescence imaging in living cells with high sensitivity, favorable selectivity, and minimal cytotoxicity.

引用

收藏

页码：4637 / 4643

页数：7

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