A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

被引:108
作者
Tan, Li [1 ]
Lin, Weiying [1 ]
Zhu, Sasa [1 ]
Yuan, Lin [1 ]
Zheng, Kaibo [1 ]
机构
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
关键词
CAPILLARY ELECTROPHORETIC DETERMINATION; SELECTIVE DETECTION; SO2; SENSITIVITY; HYDRAZINE; SENSOR;
D O I
10.1039/c4ob00132j
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Based on a novel coumarin-quinolinium platform, probe 2 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for sulfite anions. The probe exhibited a wide dynamic concentration range for sulfite anions in a PBS buffer (containing 1 mg mL(-1) BSA). More importantly, the probe was suitable for ratiometric fluorescence imaging in living cells with high sensitivity, favorable selectivity, and minimal cytotoxicity.
引用
收藏
页码:4637 / 4643
页数:7
相关论文
共 50 条
[1]   NEW SPECTROPHOTOMETRIC METHOD FOR SULFITE DETERMINATION [J].
ABDELLATIF, MS .
ANALYTICAL LETTERS, 1994, 27 (13) :2601-2614
[2]  
[Anonymous], CLIN EXP ALLERGY
[3]   Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe [J].
Au-Yeung, Ho Yu ;
Chan, Jefferson ;
Chantarojsiri, Teera ;
Chang, Christopher J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (40) :15165-15173
[4]   Novel, N-ethyl-2-styrylquinolinum iodides as fluorophores for monitoring of polymerization process, Part I [J].
Bajorek, Agnieszka ;
Kabatc, Janina ;
Paczkowski, Jerzy .
DYES AND PIGMENTS, 2009, 82 (03) :372-378
[5]   PREVALENCE OF SENSITIVITY TO SULFITING AGENTS IN ASTHMATIC-PATIENTS [J].
BUSH, RK ;
TAYLOR, SL ;
HOLDEN, K ;
NORDLEE, JA ;
BUSSE, WW .
AMERICAN JOURNAL OF MEDICINE, 1986, 81 (05) :816-820
[6]   A highly sulfite-selective ratiometric fluorescent probe based on ESIPT [J].
Chen, Song ;
Hou, Peng ;
Wang, Jianxiu ;
Song, Xiangzhi .
RSC ADVANCES, 2012, 2 (29) :10869-10873
[7]   Chromogenic and Fluorogenic Signaling of Sulfite by Selective Deprotection of Resorufin Levulinate [J].
Choi, Myung Gil ;
Hwang, Jiyoung ;
Eor, Suyoung ;
Chang, Suk-Kyu .
ORGANIC LETTERS, 2010, 12 (24) :5624-5627
[8]  
Daunoravicius Z, 2002, ELECTROPHORESIS, V23, P2439, DOI 10.1002/1522-2683(200208)23:15<2439::AID-ELPS2439>3.0.CO
[9]  
2-Z
[10]  
Frisch M. J., 2016, GAUSSIAN 16