Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo

被引：49

作者：

Dong, Yizhou ^{[1
,2
,3
]}

Eltoukhy, Ahmed A. ^{[1
]}

Alabi, Christopher A. ^{[1
,2
]}

Khan, Omar F. ^{[1
,2
]}

Veiseh, Omid ^{[1
,2
,3
]}

Dorkin, J. Robert ^{[4
]}

Sirirungruang, Sasilada ^{[5
]}

Yin, Hao ^{[1
]}

Tang, Benjamin C. ^{[1
,3
]}

Pelet, Jeisa M. ^{[1
]}

Chen, Delai ^{[1
,3
]}

Gu, Zhen ^{[1
,2
,3
]}

Xue, Yuan ^{[1
]}

Langer, Robert ^{[2
,6
,7
]}

Anderson, Daniel G. ^{[1
,2
,6
,7
]}

机构：

[1] MIT, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA

[2] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

[3] Childrens Hosp Boston, Dept Anesthesiol, Boston, MA 02115 USA

[4] MIT, Dept Biol, Cambridge, MA 02139 USA

[5] MIT, Dept Chem, Cambridge, MA 02139 USA

[6] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[7] MIT, Inst Med Engn & Sci, Cambridge, MA 02139 USA

来源：

ADVANCED HEALTHCARE MATERIALS | 2014年 / 3卷 / 09期

基金：

美国国家卫生研究院;

关键词：

lipid-like nanomaterials; siRNA; plasmid DNA; gene silencing; gene expression; COMBINATORIAL LIBRARY; SIRNA DELIVERY; DNA DELIVERY; CO-DELIVERY; NANOPARTICLES; PROGRESS; DISEASE; THERAPEUTICS; RNAI; INTERFERENCE;

D O I：

10.1002/adhm.201400054

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

[No abstract available]

引用

页码：1392 / 1397

页数：6

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