Vascular stiffness and diastolic heart failure

被引：0
作者：
Drapkina, O. M. [1 ]
Kaburova, A. N. [1 ]
机构：
[1] IM Sechenov First Moscow State Med Univ, Minist Hlth Russia, Dept Internal Med Propedeut, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2013年 / 85卷 / 11期
关键词：
vascular stiffness; diastolic chronic heart failure; fibrosis; endothelial dysfunction; inflammation; PRESERVED EJECTION FRACTION; CAROTID ARTERIAL STIFFNESS; MATRIX-METALLOPROTEINASE; CARDIOVASCULAR RISK; CURRENT PERSPECTIVES; SEX-DIFFERENCES; WALL STIFFNESS; BLOOD-PRESSURE; OLDER PATIENTS; DYSFUNCTION;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Vascular stiffness is regarded as a result of degenerative processes potentiated by aging, hypertension, and other risk factors. Central hemodynamic changes are one of the serious sequels of high arterial stiffness, which gives rise to a chain of events as a higher postload on the left ventricle, its concentric hypertrophy, diastolic dysfunction and increases the overall risk of cardiovascular events. The purpose of the review is to discuss the mechanisms of vascular stiffness, focusing on the role of this condition in the development of chronic heart failure with retained ejection fraction and its pathogenetic treatment as a future target.
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页码：75 / +
页数：7
相关论文
共 80 条
[1]   Relation of arterial stiffness to left ventricular diastolic function and cardiovascular risk prediction in patients ≥65 years of age [J].
Abhayaratna, Walter P. ;
Barnes, Marion E. ;
O'Rourke, Michael F. ;
Gersh, Bernard J. ;
Seward, James B. ;
Miyasaka, Yoko ;
Bailey, Kent R. ;
Tsang, Teresa S. M. .
AMERICAN JOURNAL OF CARDIOLOGY, 2006, 98 (10) :1387-1392
[2]  
AGEEV FT, 2010, KHRONICHESKAYA SERDE, P336
[3]  
Anderson T, 2006, WELD J, V85, P22
[4]   Matrix Metalloproteinase 2 and 9 Dysfunction Underlie Vascular Stiffness in Circadian Clock Mutant Mice [J].
Anea, Ciprian B. ;
Ali, M. Irfan ;
Osmond, Jessica M. ;
Sullivan, Jennifer C. ;
Stepp, David W. ;
Merloiu, Ana M. ;
Rudic, R. Daniel .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2010, 30 (12) :2535-U387
[5]   Implications of Vascular Aging [J].
Barodka, Viachaslau M. ;
Joshi, Brijen L. ;
Berkowitz, Dan E. ;
Hogue, Charles W., Jr. ;
Nyhan, Daniel .
ANESTHESIA AND ANALGESIA, 2011, 112 (05) :1048-1060
[6]  
Blanche C, 2010, SWISS MED WKLY, V140, P66, DOI smw-12696
[7]   Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment [J].
Borlaug, Barry A. ;
Paulus, Walter J. .
EUROPEAN HEART JOURNAL, 2011, 32 (06) :670-+
[8]   Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients - A longitudinal study [J].
Boutouyrie, P ;
Tropeano, AI ;
Asmar, R ;
Gautier, I ;
Benetos, A ;
Lacolley, P ;
Laurent, S .
HYPERTENSION, 2002, 39 (01) :10-15
[9]   Diastolic Dysfunction of Aging Is Independent of Myocardial Structure but Associated with Plasma Advanced Glycation End-Product Levels [J].
Campbell, Duncan J. ;
Somaratne, Jithendra B. ;
Jenkins, Alicia J. ;
Prior, David L. ;
Yii, Michael ;
Kenny, James F. ;
Newcomb, Andrew E. ;
Schalkwijk, Casper G. ;
Black, Mary Jane ;
Kelly, Darren J. .
PLOS ONE, 2012, 7 (11)
[10]   Age-related changes in amounts and concentrations of collagen and elastin in normotensive human thoracic aorta [J].
Cattell, MA ;
Anderson, JC ;
Hasleton, PS .
CLINICA CHIMICA ACTA, 1996, 245 (01) :73-84
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