Nrf-2-HO-1-HMGB1 axis: An important therapeutic approach for protection against myocardial ischemia and reperfusion injury

被引:23
作者
Wang, Jichun [1 ]
Hu, Xiaorong [1 ]
Jiang, H. [1 ]
机构
[1] Wuhan Univ, Dept Cardiol, Renmin Hosp, Cardiovasc Res Inst, Wuhan 430060, Peoples R China
基金
中国国家自然科学基金; 高等学校博士学科点专项科研基金;
关键词
Myocardial ischemia and reperfusion; Nrf-2; Heme oxygenase-1; Cardioprotection; Oxidative stress; P38; MAPK; IN-VIVO; RELEASE; INDUCTION; CELLS; HMGB1; SURVIVAL; NRF2; MICE; PI3K;
D O I
10.1016/j.ijcard.2013.12.273
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:223 / 224
页数:3
相关论文
共 15 条
  • [1] Heme oxygenase and the cardiovascular-renal system
    Abraham, NG
    Kappas, A
    [J]. FREE RADICAL BIOLOGY AND MEDICINE, 2005, 39 (01) : 1 - 25
  • [2] High-mobility group box-1 in ischemia-reperfusion injury of the heart
    Andrassy, Martin
    Volz, Hans C.
    Igwe, John C.
    Funke, Benjamin
    Eichberger, Sebastian N.
    Kaya, Ziya
    Buss, Sebastian
    Autschbach, Frank
    Pleger, Sven T.
    Lukic, Ivan K.
    Bea, Florian
    Hardt, Stefan E.
    Humpert, Per M.
    Bianchi, Marco E.
    Mairbaeurl, Heimo
    Nawroth, Peter P.
    Remppis, Andrew
    Katus, Hugo A.
    Bierhaus, Angelika
    [J]. CIRCULATION, 2008, 117 (25) : 3216 - 3226
  • [3] Curcurnin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
    Balogun, E
    Hoque, M
    Gong, PF
    Killeen, E
    Green, CJ
    Foresti, R
    Alam, J
    Motterlini, R
    [J]. BIOCHEMICAL JOURNAL, 2003, 371 : 887 - 895
  • [4] Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling
    Calvert, John W.
    Jha, Saurabh
    Gundewar, Susheel
    Elrod, John W.
    Ramachandran, Arun
    Pattillo, Christopher B.
    Kevil, Christopher G.
    Lefer, David J.
    [J]. CIRCULATION RESEARCH, 2009, 105 (04) : 365 - U105
  • [5] The inflammatory response in myocardial infarction
    Frangogiannis, NG
    Smith, CW
    Entman, ML
    [J]. CARDIOVASCULAR RESEARCH, 2002, 53 (01) : 31 - 47
  • [6] β1-Adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice
    Ha, Yu Mi
    Ham, Sun Ah
    Kim, Young Min
    Lee, Young Soo
    Kim, Hye Jung
    Seo, Han Geuk
    Lee, Jae Heun
    Park, Min Kyu
    Chang, Ki Churl
    [J]. BIOCHEMICAL PHARMACOLOGY, 2011, 82 (07) : 769 - 777
  • [7] HMGB1: A potential therapeutic target for myocardial ischemia and reperfusion injury
    Hu, Xiaorong
    Fu, Wenwen
    Jiang, Hong
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2012, 155 (03) : 489 - 489
  • [8] Hu XR, 2012, INT J CARDIOL, V167, P577
  • [9] Upregulation of heme oxygenase-1 expression by hydroxysafflor yellow A conferring protection from anoxia/reoxygenation-induced apoptosis in H9c2 cardiomyocytes
    Liu, Shan-Xin
    Zhang, Yu
    Wang, Yun-Fan
    Li, Xiao-Chun
    Xiang, Mei-Xiang
    Bian, Chang
    Chen, Peng
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2012, 160 (02) : 95 - 101
  • [10] Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    Scaffidi, P
    Misteli, T
    Bianchi, ME
    [J]. NATURE, 2002, 418 (6894) : 191 - 195