Novel reversible and selective nerve agent simulant detection in conjunction with superoxide "turn-on" probing

被引：44
作者：
Jang, Yoon Jeong [1 ]
Murale, Dhiraj P. [1 ]
Churchill, David G. [1 ]
机构：
[1] Korea Adv Inst Sci & Technol, Dept Chem, Mol Log Gate Lab, Taejon 305701, South Korea
来源：
ANALYST | 2014年 / 139卷 / 07期
基金：
新加坡国家研究基金会;
关键词：
FLUORESCENT; DEGRADATION; SARIN; SPECTROMETRY; PESTICIDES; CHEMISTRY; BIOLOGY; STRESS; PROBES;
D O I：
10.1039/c3an02267f
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Herein, we present fluorescein as a reversible fluorescent sensor for nerve agent simulants diethylchlorophosphate (DCP), diethyl methylphosphonate (DEMP), and diethyl cyanophosphonate (DECP). The superoxide allows for an "off-on" mechanism to regenerate fluorescein. The order of decrease in fluorescence intensity for nerve agent simulants is DCP > DEMP >> DECP.
引用
收藏
页码：1614 / 1617
页数：4
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  • [31] Design of a phosphinate-based fluorescent probe for superoxide detection in mouse peritoneal macrophages
    Xu, Kehua
    Liu, Xia
    Tang, Bo
    Yang, Guiwen
    Yang, Yong
    An, Liguo
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (05) : 1411 - 1416
  • [32] PERHYDROLYSIS OF NERVE AGENT VX
    YANG, YC
    SZAFRANIEC, LL
    BEAUDRY, WT
    BUNTON, CA
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (25) : 6964 - 6965
  • [33] Fluorescent detection of chemical warfare agents: Functional group specific ratiometric chemosensors
    Zhang, SW
    Swager, TM
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (12) : 3420 - 3421
  • [34] Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase
    Zhang, W
    Wang, TG
    Qin, LY
    Gao, HM
    Wilson, B
    Ali, SF
    Zhang, WQ
    Hong, JS
    Liu, B
    [J]. FASEB JOURNAL, 2004, 18 (01) : 589 - +
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