The relationship of Campylobacter jejuni infection and the development of Guillain-Barre syndrome

被引:29
作者
Tsang, RSW [1 ]
机构
[1] Hlth Canada, Populat & Publ Hlth Branch, Natl Microbiol Lab, Cent Nervous Syst Infect & Vaccine Preventable Ba, Winnipeg, MB R3E 3R2, Canada
关键词
D O I
10.1097/00001432-200206000-00002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Campylobacter jejuni is recognized as the most common infectious agent associated with the development of Guillain-Barre syndrome. Available information on the complete genome sequence of C. jejuni NCTC 11168 has helped researchers to identify polysaccharide capsules as well as genetic mechanisms in the synthesis of ganglioside-like cell surface molecules in this bacteria. Toxins may contribute to the host's inflammatory response seen in Guillain-Barre syndrome.
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页码:221 / 228
页数:8
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