Case History: Discovery of Ixabepilone (IXEMPRA™), a First-in-Class Epothilone Analog for Treatment of Metastatic Breast Cancer

被引：10
作者：
Borzilleri, Robert M. [1 ]
Vite, Gregory D. [1 ]
机构：
[1] Bristol Myers Squibb Co, R&D, Princeton, NJ 08543 USA
来源：
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 44 | 2009年 / 44卷
关键词：
MICROTUBULE-STABILIZING AGENTS; BIOSYNTHETIC GENE-CLUSTER; SORANGIUM-CELLULOSUM; B ANALOG; CLINICAL DEVELOPMENT; HETEROLOGOUS EXPRESSION; TUBULIN POLYMERIZATION; BIOLOGICAL-ACTIVITY; ANTITUMOR-ACTIVITY; SOLID TUMORS;
D O I：
10.1016/S0065-7743(09)04415-7
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：301 / 322
页数：22
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