Prostate cancer pathology: What has changed in the last 5 years

被引:11
作者
Cimadamore, Alessia [1 ]
Scarpelli, Marina [1 ]
Raspollini, Maria Rosaria [2 ]
Doria, Andrea [1 ]
Galosi, Andrea Benedetto [3 ]
Massari, Francesco [4 ]
Di Nunno, Vincenzo [4 ]
Cheng, Liang [5 ]
Lopez-Beltran, Antonio [6 ]
Montironi, Rodolfo [1 ]
机构
[1] Marche Polytech Univ, Sect Pathol Anat, Sch Med, United Hosp, Via Conca 71, I-60126 Ancona, Italy
[2] Careggi Univ Hosp, Histopathol & Mol Diagnost, Florence, Italy
[3] Marche Polytech Univ, Inst Urol, Sch Med, United Hosp, Ancona, Italy
[4] Policlin St Orsola Malpighi Hosp, Div Oncol, Bologna, Italy
[5] Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA
[6] Univ Cordoba, Dept Pathol & Surg, Fac Med, Cordoba, Spain
关键词
Prostate cancer; classification; grading; staging; clinically significant PCa; ISUP CONSENSUS-CONFERENCE; ATYPICAL CRIBRIFORM LESIONS; INTRADUCTAL-CARCINOMA; RADICAL-PROSTATECTOMY; INTERNATIONAL-SOCIETY; PROGNOSTIC MODEL; NEEDLE-BIOPSY; ADENOCARCINOMA; CLASSIFICATION; PREDICTS;
D O I
10.1177/0391560319876821
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Prostate cancer is the most frequent non-cutaneous malignancy in men in the United States. In the last few years, many recommendations have been made available from the 2014 International Society of Urologic Pathology consensus conference, 2016 World Health Organization blue book and 2018 8th edition of American Joint Committee on Cancer Staging System. Here, we focus on four topics which are considered relevant on the basis of their common appearance in routine practice, clinical importance and 'need to improve communication between pathology reports and clinicians': prostate cancer classification, prostate cancer grading, prostate cancer staging, and current definition of clinically significant prostate cancer. Tissue biomarkers that can predict significant disease and/or upgrading and tissue-based genomics for the purpose of diagnosis and prognosis are mentioned briefly.
引用
收藏
页码:3 / 10
页数:8
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