Gain-Scheduled Oxygen Concentration Control System for a Bioreactor

被引：5

作者：

Arevalo, H. ^{[1
]}

Sanchez, F. ^{[1
]}

Ruiz, F. ^{[2
]}

Guerrero, D. ^{[1
]}

Patino, D. ^{[1
]}

Almeciga-Diaz, C. ^{[3
,4
,5
]}

Rodriguez-Lopez, A. ^{[3
]}

机构：

[1] Pontificia Univ Javeriana, Bogota, Colombia

[2] Pontificia Univ Javeriana, Fac Ingn, Bogota, Colombia

[3] Pontificia Univ Javeriana, Ciencias Biol, Bogota, Colombia

[4] Pontificia Univ Javeriana, Fac Ciencias, Bogota, Colombia

[5] Pontificia Univ Javeriana, IEIM, Bogota, Colombia

来源：

IEEE LATIN AMERICA TRANSACTIONS | 2018年 / 16卷 / 11期

关键词：

Gain-scheduling control; Bioreactor control; Dissolved oxygen control; ADAPTIVE PREDICTIVE CONTROL; STRATEGY; MODEL;

D O I：

10.1109/TLA.2018.8795109

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

This article presents a multi-variable control strategy for the regulation of Dissolved Oxygen Concentration in a stirred laboratory-scale bioreactor. The controller manipulates the airflow and agitation speed in the reactor. Departing from a mechanistic model that relates the manipulated variables and the oxygen transfer coefficient, linearized local models of the process are obtained. It is observed that there is high variability in the process behavior with the operating point. Then, a Gain-Scheduled controller is proposed. The strategy varies the agitation speed employing a PI control law and varies the air flow according to a switching law that detects saturations in the manipulated variables. The proposed strategy is evaluated in simulation and implemented in a real bioreactor. Results show that the strategy is able to regulate the oxygen concentration in a wide range of operating conditions.

引用

页码：2689 / 2697

页数：9

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