Physical activity and dementia: The need for prevention trials

被引：46

作者：

Barnes, Deborah E.

Whitmer, Rachel A.

Yaffe, Kristine

机构：

[1] Univ Calif San Francisco, Dept Psychiat, San Francisco, CA 94121 USA

[2] San Francisco VA Med Ctr, San Francisco, CA USA

[3] Kaiser Permanente, Div Res, Oakland, CA USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2007年 / 35卷 / 01期

关键词：

exercise; fitness; cognitive decline; aged; epidemiology; mechanisms;

D O I：

10.1097/JES.0b013e31802d6bc2

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Dementia is a common and debilitating disease that will increase dramatically for the next 50 years unless a prevention or treatment is identified. This review summarizes the evidence that physical activity is associated with a reduced risk of dementia in older adults and recommends that prevention trials be performed to determine whether this association is causal.

引用

页码：24 / 29

页数：6

共 25 条

[1] Walking and dementia in physically capable elderly men
Abbott, RD
White, LR
Ross, GW
Masaki, KH
Curb, JD
Petrovitch, H
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (12): : 1447 - 1453
[2] Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
Adlard, PA
Perreau, VM
Pop, V
Cotman, CW
[J]. JOURNAL OF NEUROSCIENCE, 2005, 25 (17) : 4217 - 4221
[3] [Anonymous], 1996, Physical activity and health: A report of the Surgeon General
[4] A longitudinal study of cardiorespiratory fitness and cognitive function in healthy older adults
Barnes, DE
Yaffe, K
Satariano, WA
Tager, IB
[J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2003, 51 (04) : 459 - 465
[5] Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
Brookmeyer, R
Gray, S
Kawas, C
[J]. AMERICAN JOURNAL OF PUBLIC HEALTH, 1998, 88 (09) : 1337 - 1342
[6] Fitness effects on the cognitive function of older adults: A meta-analytic study
Colcombe, S
Kramer, AF
[J]. PSYCHOLOGICAL SCIENCE, 2003, 14 (02) : 125 - 130
[7] Neurocognitive aging and cardiovascular fitness - Recent findings and future directions
Colcombe, SJ
Kramer, AF
McAuley, E
Erickson, KI
Scalf, P
[J]. JOURNAL OF MOLECULAR NEUROSCIENCE, 2004, 24 (01) : 9 - 14
[8] Colcombe SJ, 2003, J GERONTOL A-BIOL, V58, P176
[9] Exercise: a behavioral intervention to enhance brain health and plasticity
Cotman, CW
Berchtold, NC
[J]. TRENDS IN NEUROSCIENCES, 2002, 25 (06) : 295 - 301
[10] Does exercise reduce inflammation? Physical activity and C-reactive protein among US adults
Ford, ES
[J]. EPIDEMIOLOGY, 2002, 13 (05) : 561 - 568

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