Application of MSI in MRI-negative focal cortical dysplasia patients with epilepsy

被引:0
作者
Sun, Jilin [1 ]
Jia, Xiuchuan [1 ]
Liu, Xi [1 ]
Wu, Jie [1 ]
Li, Sumin [1 ]
机构
[1] Hebei Gen Hosp, Dept Radiol, 348 Heping Rd, Shijiazhuang 050000, Peoples R China
关键词
Focal cortical dysplasia; magnetic resonance imaging; epilepsy; magnetic source imaging; INTRINSIC EPILEPTOGENICITY; MEG; EEG; MAGNETOENCEPHALOGRAPHY; ELECTROCORTICOGRAPHY; CLASSIFICATION; FEATURES;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Focal cortical dysplasia (FCD) is the most common cause of intractable epilepsy in children and adolescent. Purpose: To evaluate the application value of magnetic source imaging (MSI) in treatment of magnetic resonance imaging (MRI)-negative FCD patients with epilepsy. Methods: MSI characteristics of 17 cases of MRI-negative focal cortical dysplasia patients with epilepsy were retrospectively analyzed. All patients were treated by surgery. Results: In 17 patients, there were 3 cases of FCD Ia, 7 cases of FCDIb, 3 cases of FCDIIa and 4 cases of FCDIIb. FCD was located at temporal lobe in 8 cases, occipital lobe in 3 cases, frontal lobe in 2 cases and two lobes in 4 cases. In follow-up, 14 patients obtained satisfied curative effect. 1 patient was improved significantly and 2 patients were fine. The concordance between MSI and electrocorticogram in localizing epileptogenic foci was 65%. Conclusion: MSI is a new prospective noninvasive functional neuroimaging technique for identifying and delineating epileptogenic foci in MRI-negative FCD patients.
引用
收藏
页码:18427 / 18433
页数:7
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