Application of MSI in MRI-negative focal cortical dysplasia patients with epilepsy

被引：0
作者：
Sun, Jilin [1 ]
Jia, Xiuchuan [1 ]
Liu, Xi [1 ]
Wu, Jie [1 ]
Li, Sumin [1 ]
机构：
[1] Hebei Gen Hosp, Dept Radiol, 348 Heping Rd, Shijiazhuang 050000, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2015年 / 8卷 / 10期
关键词：
Focal cortical dysplasia; magnetic resonance imaging; epilepsy; magnetic source imaging; INTRINSIC EPILEPTOGENICITY; MEG; EEG; MAGNETOENCEPHALOGRAPHY; ELECTROCORTICOGRAPHY; CLASSIFICATION; FEATURES;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Background: Focal cortical dysplasia (FCD) is the most common cause of intractable epilepsy in children and adolescent. Purpose: To evaluate the application value of magnetic source imaging (MSI) in treatment of magnetic resonance imaging (MRI)-negative FCD patients with epilepsy. Methods: MSI characteristics of 17 cases of MRI-negative focal cortical dysplasia patients with epilepsy were retrospectively analyzed. All patients were treated by surgery. Results: In 17 patients, there were 3 cases of FCD Ia, 7 cases of FCDIb, 3 cases of FCDIIa and 4 cases of FCDIIb. FCD was located at temporal lobe in 8 cases, occipital lobe in 3 cases, frontal lobe in 2 cases and two lobes in 4 cases. In follow-up, 14 patients obtained satisfied curative effect. 1 patient was improved significantly and 2 patients were fine. The concordance between MSI and electrocorticogram in localizing epileptogenic foci was 65%. Conclusion: MSI is a new prospective noninvasive functional neuroimaging technique for identifying and delineating epileptogenic foci in MRI-negative FCD patients.
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页码：18427 / 18433
页数：7
相关论文
共 19 条
[1]   EEG and MEG source analysis of single and averaged interictal spikes reveals intrinsic epileptogenicity in focal cortical dysplasia [J].
Bast, T ;
Oezkan, O ;
Rona, S ;
Stippich, C ;
Seitz, A ;
Rupp, A ;
Fauser, S ;
Zentner, J ;
Rating, D ;
Scherg, M .
EPILEPSIA, 2004, 45 (06) :621-631
[2]   The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission [J].
Bluemcke, Ingmar ;
Thom, Maria ;
Aronica, Eleonora ;
Armstrong, Dawna D. ;
Vinters, Harry V. ;
Palmini, Andre ;
Jacques, Thomas S. ;
Avanzini, Giuliano ;
Barkovich, A. James ;
Battaglia, Giorgio ;
Becker, Albert ;
Cepeda, Carlos ;
Cendes, Fernando ;
Colombo, Nadia ;
Crino, Peter ;
Cross, J. Helen ;
Delalande, Olivier ;
Dubeau, Francois ;
Duncan, John ;
Guerrini, Renzo ;
Kahane, Philippe ;
Mathern, Gary ;
Najm, Imad ;
Ozkara, Cigdem ;
Raybaud, Charles ;
Represa, Alfonso ;
Roper, Steven N. ;
Salamon, Noriko ;
Schulze-Bonhage, Andreas ;
Tassi, Laura ;
Vezzani, Annamaria ;
Spreafico, Roberto .
EPILEPSIA, 2011, 52 (01) :158-174
[3]  
Ebersole JS, 1997, EPILEPSIA S4, V38, P1
[4]   Focal Cortical Dysplasia [J].
Gaitanis, John N. ;
Donahue, John .
PEDIATRIC NEUROLOGY, 2013, 49 (02) :79-87
[5]   Voxel-based 3D MRI analysis helps to detect subtle forms of subcortical band heterotopia [J].
Huppertz, Hans-Juergen ;
Wellmer, Joerg ;
Staack, Anke Maren ;
Altenmueller, Dirk-Matthias ;
Urbach, Horst ;
Kroell, Judith .
EPILEPSIA, 2008, 49 (05) :772-785
[6]   Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia [J].
Ishii, Ryouhei ;
Canuet, Leonides ;
Ochi, Ayako ;
Xiang, Jing ;
Imai, Katsumi ;
Chan, Derrick ;
Iwase, Masao ;
Takeda, Masatoshi ;
Snead, O. Carter, III ;
Otsubo, Hiroshi .
EPILEPSY RESEARCH, 2008, 81 (2-3) :228-232
[7]   Seizure outcome of infantile spasms with focal cortical dysplasia [J].
Kang, Joon Won ;
Rhie, Seon Kyeong ;
Yu, Rita ;
Eom, Soyong ;
Hong, William ;
Kim, Shin Hye ;
Kang, Hoon-Chul ;
Lee, Joon Soo ;
Lee, Young-Mock ;
Kim, Heung Dong .
BRAIN & DEVELOPMENT, 2013, 35 (08) :816-820
[8]   Magnetic source imaging (MSI) in children with neocortical epilepsy: Surgical outcome association with 3D post-resection analysis [J].
Kim, Hyunmi ;
Kankirawatana, Pongkiat ;
Killen, Jeff ;
Harrison, Allan ;
Oh, Ahyuda ;
Rozzelle, Curtis ;
Blount, Jeffrey ;
Knowlton, Robert .
EPILEPSY RESEARCH, 2013, 106 (1-2) :164-172
[9]   Different features of histopathological subtypes of pediatric focal cortical dysplasia [J].
Krsek, Pavel ;
Maton, Bruno ;
Korman, Brandon ;
Pacheco-Jacome, Esperanza ;
Jayakar, Prasanna ;
Dunoyer, Catalina ;
Rey, Gustavo ;
Morrison, Glenn ;
Ragheb, John ;
Vinters, Harry V. ;
Resnick, Trevor ;
Duchowny, Michael .
ANNALS OF NEUROLOGY, 2008, 63 (06) :758-769
[10]  
Lewine JD, 1995, MAGNETOENCEPHALOGRAP, P369
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