Nitric oxide, health and disease

被引:31
作者
Bucalen Ferrari, Carlos Kusano [1 ]
Franca, Eduardo Luzia [1 ]
Honorio-Franca, Adenilda Cristina [1 ]
机构
[1] Fed Univ Mato Grosso UFMT, Campus Univ Araguaia, Biomed Res Grp, BR-78698000 Pontal Do Araguaia, Brazil
关键词
peroxynitrite; cancer; cardiovascular diseases; phagocytosis; diabetes mellitus; infection; NITROSATIVE STRESS; LIPID-PEROXIDATION; TRYPANOSOMA-CRUZI; OXIDATIVE STRESS; BLOOD-PRESSURE; ENDOTHELIAL DYSFUNCTION; PLASMODIUM-FALCIPARUM; AIRWAY INFLAMMATION; MURINE MACROPHAGES; SYNTHASE INHIBITOR;
D O I
10.32725/jab.2009.019
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Nitric oxide is a gaseous substance which possesses many important physiological characteristics ranging from its action as a natural immune mechanism to endothelial control of blood pressure. However, it can also generate nitrogen reactive species (peroxynitrite and others), which are involved as a cause of or a consequence of many diseases. This article updates and summarizes the physiological and pathophysiological roles of nitric oxide.
引用
收藏
页码:163 / 173
页数:11
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