Antagonists of protein-protein interactions

被引：220

作者：

Cochran, AG ^{[1
]}

机构：

[1] Genentech Inc, Dept Prot Engn, San Francisco, CA 94080 USA

来源：

CHEMISTRY & BIOLOGY | 2000年 / 7卷 / 04期

关键词：

D O I：

10.1016/S1074-5521(00)00106-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Protein-protein interactions are often attractive, but not straightforward, targets for disease therapy. Two strategies for identifying inhibitors of these interactions, peptide phage display and high-throughput screening, have recently shown new promise.

引用

页码：R85 / R94

页数：10

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