Presence of rare hepatitis C virus subtypes, 2j, 2k, and 2r in Mexico City as identified by sequencing

被引：6

作者：

Antonio Uribe-Noguez, Luis ^{[1
,2
]}

Ocana-Mondragon, Alicia ^{[1
]}

Antonio Mata-Marin, Jose ^{[3
]}

Elena Gomez-Torres, Maria ^{[4
]}

Maria Ribas-Aparicio, Rosa ^{[2
]}

de la Luz Martinez-Rodriguez, Maria ^{[1
]}

机构：

[1] Inst Mexicano Seguro Social, Hosp Infectol, Ctr Med Nacl La Raza, Unidad Invest Med Inmunol & Infectol, Ave Jacarandas Esquina Vallejo S-N, Cdmx 02990, Mexico

[2] Inst Politecn Nacl, Dept Microbiol, Programa Biomed & Biotecnol Mol, Escuela Nacl Ciencias Biol, Cdmx, Mexico

[3] Inst Mexicano Seguro Social, Hosp Infectol, Dept Enfermedades Infecciosas, Ctr Med Nacl La Raza, Cdmx, Mexico

[4] Inst Mexicano Seguro Social, Hosp Infectol, Ctr Med Nacl La Raza, Lab Urgencias, Cdmx, Mexico

来源：

JOURNAL OF MEDICAL VIROLOGY | 2018年 / 90卷 / 07期

关键词：

epidemiology; evolution; genetic variability; hepatitis C virus; virus classification; MOLECULAR EPIDEMIOLOGY; GLOBAL EPIDEMIOLOGY; GENOTYPES; INFECTION; HISTORY;

D O I：

10.1002/jmv.25070

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT-1a, nine with GT-2b and four with GT-3a. Two rare subtypes were detected: GT-2j in two patients and GT-2r in one patient. Three patients had mixed infections: one with GT-2k + 2j and two with GT-1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.

引用

页码：1277 / 1282

页数：6

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