Preparation, characterization and antimicrobial activity of chitosan - Zn complex

被引：344

作者：

Wang, X ^{[1
]}

Du, YM ^{[1
]}

Liu, H ^{[1
]}

机构：

[1] Wuhan Univ, Dept Environm Sci, Wuhan 430072, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2004年 / 56卷 / 01期

基金：

中国国家自然科学基金;

关键词：

chitosan-Zn; complexes; antimicrobial activity;

D O I：

10.1016/j.carbpol.2003.11.007

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Five chitosan-zinc complexes with different zinc content were prepared and characterized by FT-IR, XRD, AAS and elemental analysis. It was found that the complexes with different zinc content had different molecule structure. Three possible structures corresponding to different chelate ratios were proposed and preliminarily complexation mechanisms were discussed. In vitro antimicrobial activities of complexes were evaluated against 11 species of bacteria and fungi. The complexes showed wide spectrum of effective antimicrobial activities, which were 2-8 times and 4-16 times higher than those of chitosan and zinc sulfate, respectively, and improved with increasing content of zinc ions. The complexes had a better antibacterial activity than antifungal activity, and showed excellent activity particularly against E. Coli. and Corynebacterial both with a MIC value of 0.000313% (CS-Zn w/v). (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：21 / 26

页数：6

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