Reconstruction of the refractive index gradient by x-ray diffraction enhanced computed tomography

被引:20
作者
Wang, Junyue
Zhu, Peiping [1 ]
Yuan, Qingxi
Huang, Wanxia
Shu, Hang
Chen, Bo
Hu, Tiandou
Wu, Ziyu
机构
[1] Chinese Acad Sci, Beijing Synchrotron Radiat Facil, Inst High Energy Phys, Beijing 100049, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China
[3] Natl Ctr NanoSci & Technol, Beijing 100080, Peoples R China
[4] Univ Sci & Technol China, Dept Phys, Hefei 230026, Peoples R China
关键词
D O I
10.1088/0031-9155/51/14/007
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The computed tomography technique cannot easily be extended to diffraction enhanced imaging (DEI) because, while from DEI we may extract the refractive index gradient in one dimension, from the conventional CT reconstruction algorithm we may reconstruct only a scalar quantity. However, recently we showed that changing the direction of the scan axis, and collecting a set of data related to the three-dimensional distribution of the refractive index gradient of the sample, a CT image was obtained. The algorithm we used is based on the conventional CT algorithm but with a specific pre-processing of the projection data. The mathematical framework of the procedure and a simple CT experiment are presented and discussed.
引用
收藏
页码:3391 / 3396
页数:6
相关论文
共 26 条
[1]   Diffraction enhanced x-ray imaging [J].
Chapman, D ;
Thomlinson, W ;
Johnston, RE ;
Washburn, D ;
Pisano, E ;
Gmur, N ;
Zhong, Z ;
Menk, R ;
Arfelli, F ;
Sayers, D .
PHYSICS IN MEDICINE AND BIOLOGY, 1997, 42 (11) :2015-2025
[2]   Holotomography: Quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays [J].
Cloetens, P ;
Ludwig, W ;
Baruchel, J ;
Van Dyck, D ;
Van Landuyt, J ;
Guigay, JP ;
Schlenker, M .
APPLIED PHYSICS LETTERS, 1999, 75 (19) :2912-2914
[3]   PHASE-CONTRAST IMAGING OF WEAKLY ABSORBING MATERIALS USING HARD X-RAYS [J].
DAVIS, TJ ;
GAO, D ;
GUREYEV, TE ;
STEVENSON, AW ;
WILKINS, SW .
NATURE, 1995, 373 (6515) :595-598
[4]   Computed tomography of x-ray index of refraction using the diffraction enhanced imaging method [J].
Dilmanian, FA ;
Zhong, Z ;
Ren, B ;
Wu, XY ;
Chapman, LD ;
Orion, I ;
Thomlinson, WC .
PHYSICS IN MEDICINE AND BIOLOGY, 2000, 45 (04) :933-946
[5]   Imaging lobular breast carcinoma:: comparison of synchrotron radiation DEI-CT technique with clinical CT, mammography and histology [J].
Fiedler, S ;
Bravin, A ;
Keyriläinen, J ;
Fernández, M ;
Suortti, P ;
Thomlinson, W ;
Tenhunen, M ;
Virkkunen, P ;
Karjalainen-Lindsberg, ML .
PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (02) :175-188
[6]   Image deblurring by means of defocus [J].
Gureyev, TE ;
Stevenson, AW ;
Nesterets, YI ;
Wilkins, SW .
OPTICS COMMUNICATIONS, 2004, 240 (1-3) :81-88
[7]   Diffraction enhanced imaging contrast mechanisms in breast cancer specimens [J].
Hasnah, MO ;
Zhong, Z ;
Oltulu, O ;
Pisano, E ;
Johnston, RE ;
Sayers, D ;
Thomlinson, W ;
Chapman, D .
MEDICAL PHYSICS, 2002, 29 (10) :2216-2221
[8]   Angle-resolved x-ray imaging using a resolution-tunable double-crystal analyser [J].
Hirano, K .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2003, 36 (13) :1469-1472
[9]   X-ray optics for observing dark-field and bright-field refraction-contrast images [J].
Hirano, K ;
Maksimenko, A ;
Sugiyama, H ;
Ando, M .
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS, 2002, 41 (5B) :L595-L598
[10]   Coherence-enhanced synchrotron radiology: Refraction versus diffraction mechanisms [J].
Hwu, Y ;
Hsieh, HH ;
Lu, MJ ;
Tsai, WL ;
Lin, HM ;
Goh, WC ;
Lai, B ;
Je, JH ;
Kim, CK ;
Noh, DY ;
Youn, HS ;
Tromba, G ;
Margaritondo, G .
JOURNAL OF APPLIED PHYSICS, 1999, 86 (08) :4613-4618