A novel route to the synthesis of 3-pyridine carboxaldehydes by Vilsmeier reagent

被引:12
作者
Amaresh, RR [1 ]
Perumal, PT [1 ]
机构
[1] Cent Leather Res Inst, Div Organ Chem, Madras 600020, Tamil Nadu, India
关键词
D O I
10.1080/00397910008086865
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2-Chloro-5-aryl-3-pyridine carboxaldehydes are obtained by Vilsmeier reaction of 4-aryl-3-buten-2-one oxime. The suspected intermediate N-(2-arylethenyl)acetamides also give the same 2-chloro-5aryl-3-pyridine carboxaldehydes under identical reaction condition.
引用
收藏
页码:2269 / 2274
页数:6
相关论文
共 16 条
[1]   A novel one-pot synthesis of 2-aminoquinolines from arylazidoketones by cyclization under Vilsmeier conditions [J].
Amaresh, RR ;
Perumal, PT .
TETRAHEDRON, 1998, 54 (47) :14327-14340
[2]   A new route to the synthesis of 4-chloro-3-methylquinolines from 1-(2-aminophenyl)propanones using Vilsmeier reagent. [J].
Amaresh, RR ;
Perumal, PT .
SYNTHETIC COMMUNICATIONS, 1997, 27 (02) :337-343
[3]  
Amaresh RR, 1997, INDIAN J CHEM B, V36, P541
[4]   THE BECKMANN REARRANGEMENT OF SUBSTITUTED BENZYLIDENEACETONE OXIMES [J].
CORBETT, RE ;
DAVEY, CL .
JOURNAL OF THE CHEMICAL SOCIETY, 1955, :296-297
[5]   SYNTHESIS OF TETRASUBSTITUTED PYRIDINES FROM N,N-DIALKYLCYANOACETAMIDES [J].
COSSEY, AL ;
HARRIS, RLN ;
HUPPATZ, JL ;
PHILLIPS, JN .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1972, 11 (12) :1098-1099
[6]  
Jones G., 1997, ORG REACTIONS, V49, P1
[7]  
Jutz C., 1976, ADV ORG CHEM, V9, P225
[8]  
KOPP FD, 1989, EUR J MED CHEM, V24, P313
[9]   Dimerization of substituted 2-aminobenzoic acids under Vilsmeier conditions: A novel route to the synthesis of 4-(3H)-quinazolinones. [J].
Majo, VJ ;
Perumal, PT .
TETRAHEDRON LETTERS, 1996, 37 (28) :5015-5018
[10]   A NEW ROUTE TO THE SYNTHESIS OF N-FORMYL LACTAMS USING VILSMEIER REAGENT [J].
MAJO, VJ ;
VENUGOPAL, M ;
PRINCE, AAM ;
PERUMAL, PT .
SYNTHETIC COMMUNICATIONS, 1995, 25 (23) :3863-3868