Ultra-performance liquid chromatography-tandem mass spectrometry:: A novel challenge in multiresidue pesticide analysis in food

被引：61
作者：
Kovalczuk, Tomas [1 ]
Jech, Martin [1 ]
Poustka, Jan [1 ]
Hajslova, Jana [1 ]
机构：
[1] Dept Food Chem & Anal, Inst Chem Technol, Prague 16628 6, Czech Republic
来源：
ANALYTICA CHIMICA ACTA | 2006年 / 577卷 / 01期
关键词：
ultra-performance liquid chromatography; high-performance liquid chromatography; tandem quadrupole mass spectrometry; multiresidue; pesticides; food analysis;
D O I：
10.1016/j.aca.2006.06.023
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Potential of ultra-performance liquid chromatography (UPLC) separation strategy coupled with tandem (in space) mass spectrometric detection (MS/MS) in multiresidue pesticide analysis was critically assessed. Performance parameters such as number of theoretical plates, height of theoretical plate, peak symmetry and peak capacity were measured/calculated on the basis of data generated by analysis of apple extracts containing 17 (semi)polar pesticides representing various classes of active ingredients of widely used crop protective preparations. Ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) procedure provided improved chromatographic parameters resulting in significantly increased sample throughput including lower solvent consumption and lower limits of quantitation (LOQs) for most of target analytes compared to common method employing conventional high-performance liquid chromatography (HPLC) separation. (c) 2006 Elsevier B.V. All rights reserved.
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页码：8 / 17
页数：10
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