IL-17 and "TH2-high" asthma: Adding fuel to the fire?

被引:14
作者
Bhakta, Nirav R. [1 ]
Erle, David J. [1 ]
机构
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
关键词
Asthma: cellular/molecular mechanisms; cytokines; endotype; IL-13; IL-17; INNATE LYMPHOID-CELLS; AIRWAY HYPERRESPONSIVENESS; T-CELLS; INFLAMMATION; PRODUCE; SUBSET;
D O I
10.1016/j.jaci.2014.07.034
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:1187 / 1188
页数:2
相关论文
共 15 条
[11]   Th17-mediated inflammation in asthma [J].
Newcomb, Dawn C. ;
Peebles, R. Stokes, Jr. .
CURRENT OPINION IN IMMUNOLOGY, 2013, 25 (06) :755-760
[12]   Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids [J].
Ramesh, Radha ;
Kozhaya, Lina ;
McKevitt, Kelly ;
Djuretic, Ivana M. ;
Carlson, Thaddeus J. ;
Quintero, Maria A. ;
McCauley, Jacob L. ;
Abreu, Maria T. ;
Unutmaz, Derya ;
Sundrud, Mark S. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2014, 211 (01) :89-104
[13]   Type 2 innate lymphoid cells: new players in asthma and allergy [J].
Scanlon, Seth T. ;
McKenzie, Andrew N. J. .
CURRENT OPINION IN IMMUNOLOGY, 2012, 24 (06) :707-712
[14]   A novel subset of CD4+ TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma [J].
Wang, Yui-Hsi ;
Voo, Kui Shin ;
Liu, Bo ;
Chen, Chun-Yu ;
Uygungil, Burcin ;
Spoede, William ;
Bernstein, Jonathan A. ;
Huston, David P. ;
Liu, Yong-Jun .
JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (11) :2479-2491
[15]   T-helper Type 2-driven Inflammation Defines Major Subphenotypes of Asthma [J].
Woodruff, Prescott G. ;
Modrek, Barmak ;
Choy, David F. ;
Jia, Guiquan ;
Abbas, Alexander R. ;
Ellwanger, Almut ;
Arron, Joseph R. ;
Koth, Laura L. ;
Fahy, John V. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 180 (05) :388-395