Mechanisms and clinical relevance of the interaction between metamizole and acetylsalicylic acid - a review

被引：0
|
作者：
Fleck, S. [1 ]
Rumpold-Seitlinger, G. [1 ]
Bornemann-Cimenti, H. [1 ]
机构：
[1] Med Univ Graz, Klin Abt Spezielle Anasthesiol Schmerz & Intens M, Auenbruggerpl 29, A-8036 Graz, Austria
来源：
ANASTHESIOLOGIE & INTENSIVMEDIZIN | 2018年 / 59卷
关键词：
Dipyrone; Aspirin; Platelet Aggregation; Anti-Inflammatory Agents; nonsteroidal; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MYOCARDIAL-INFARCTION; DIPYRONE METAMIZOLE; SALICYLIC-ACID; ASPIRIN; RISK; INHIBITION; ANALGESICS; MEDICATION;
D O I：
暂无
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
An interaction between acetylsalicylic acid and metamizole, which, analogous to the interaction between aspirin and nonsteroidal antirheumatic drugs, can lead to a lack of thrombocyte aggregation inhibition, has already been postulated 10 years ago based on in-vitro experiments. Subsequent studies identified the underlying mechanisms. Current epidemiological data highlight the clinical relevance of this interaction. The aim of this work is to provide an overview of the mechanism and the clinical evidence of this interaction.
引用
收藏
页码：180 / 185
页数：8
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