CLINICAL, ELECTROPHYSIOLOGIC, AND IMAGING FEATURES OF ZOSTER-ASSOCIATED LIMB PARESIS

被引:29
作者
Jones, Lyell K., Jr. [1 ]
Reda, Haatem [1 ]
Watson, James C. [1 ]
机构
[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA
关键词
Herpes zoster; zoster paresis; zoster-associated limb paresis; postherpetic neuralgia; infectious neuropathy; HERPES-ZOSTER; POSTHERPETIC NEURALGIA; NEUROPATHY; VACCINE;
D O I
10.1002/mus.24141
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Paresis is a long-recognized complication of herpes zoster, but there has been comparatively little study of zoster-associated limb paresis (ZALP). Methods: In this study we reviewed 49 Mayo Clinic patients with ZALP. Results: The mean age of onset was 71 years, 67% were men, and the lower limb was affected in 55%. The mean weakness score was 2.0 (0 = normal strength, 4 = plegia). Most patients developed postherpetic neuralgia (PHN, 92% at 1 month and 65% at 3 months), and the average minimum duration of weakness was 193 days. ZALP was caused by radiculopathy (37%), plexopathy (41%), mononeuropathy (14%), and radiculoplexus neuropathy (8%). MRI demonstrated nerve enlargement, T2 signal prolongation, or enhancement in a majority (64%) of affected plexi and peripheral nerves. Conclusions: ZALP is associated with considerable weakness. It typically lasts at least several months, localizes to plexus or peripheral nerve in 63%, and is associated with high rates of PHN.
引用
收藏
页码:177 / 185
页数:9
相关论文
共 27 条
[1]   Brachial neuritis caused by varicella-zoster diagnosed by changes in brachial plexus on MRI [J].
Ayoub, Tariq ;
Raman, Vivek ;
Chowdhury, Muhammad .
JOURNAL OF NEUROLOGY, 2010, 257 (01) :1-4
[2]  
Broadbent WH, 1866, Br Med J., V2, P460
[3]   FOCAL WEAKNESS FOLLOWING HERPES-ZOSTER [J].
COCKERELL, OC ;
ORMEROD, IEC .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1993, 56 (09) :1001-1003
[4]  
Denny-Brown D., 1944, ARCH NEUROL AND PSYCHIAT, V51, P216
[5]   THE ROCHESTER DIABETIC NEUROPATHY STUDY - DESIGN, CRITERIA FOR TYPES OF NEUROPATHY, SELECTION BIAS, AND REPRODUCIBILITY OF NEUROPATHIC TESTS [J].
DYCK, PJ ;
KRATZ, KM ;
LEHMAN, KA ;
KARNES, JL ;
MELTON, LJ ;
OBRIEN, PC ;
LITCHY, WJ ;
WINDEBANK, AJ ;
SMITH, BE ;
LOW, PA ;
SERVICE, FJ ;
RIZZA, RA ;
ZIMMERMAN, BR .
NEUROLOGY, 1991, 41 (06) :799-807
[6]  
Fabian VA, 1997, CLIN NEUROPATHOL, V16, P61
[7]   Postherpetic neuralgia: Irritable nociceptors and deafferentation [J].
Fields, HL ;
Rowbotham, M ;
Baron, R .
NEUROBIOLOGY OF DISEASE, 1998, 5 (04) :209-227
[8]   Neurologic complications of the reactivation of varicella-zoster virus. [J].
Gilden, DH ;
Kleinschmidt-DeMasters, BK ;
LaGuardia, JJ ;
Mahalingam, R ;
Cohrs, RJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (09) :635-645
[9]   Herpes Zoster [J].
Cohen, Jeffrey I. .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (03) :255-263
[10]   SEGMENTAL MOTOR INVOLVEMENT IN HERPES-ZOSTER - AN EMG STUDY [J].
GREENBERG, MK ;
MCVEY, AL ;
HAYES, T .
NEUROLOGY, 1992, 42 (05) :1122-1123