Nanoscale UiO-MOF-based luminescent sensors for highly selective detection of cysteine and glutathione and their application in bioimaging

被引：125
作者：
Li, Yan-An [1 ]
Zhao, Chao-Wei [1 ]
Zhu, Neng-Xiu [1 ]
Liu, Qi-Kui [1 ]
Chen, Gong-Jun [1 ]
Liu, Jian-Biao [1 ]
Zhao, Xiao-Dong [1 ,2 ]
Ma, Jian-Ping [1 ]
Zhang, Shaojun [3 ]
Dong, Yu-Bin [1 ]
机构：
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Collaborat Innovat Ctr Functionalized Probes Chem, Key Lab Mol & Nano Probes,Minist Educ, Jinan 250014, Peoples R China
[2] Shandong Acad Med Sci, Inst Basic Med, Jinan 250062, Peoples R China
[3] Qianfoshan Hosp Shandong Prov, Jinan 250014, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 100期
关键词：
METAL-ORGANIC FRAMEWORKS; FLUORESCENCE TURN-ON; PROBE; THIOLS; EFFICACY; CELLS;
D O I：
10.1039/c5cc07783d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a practical approach, the first of its kind, to construct nanoscale UiO-type metal-organic framework (Mi-UiO-66 and Mi-UiO-67) fluorescent probes for the detection of Cys and GSH. They showed high sensitivity (10(-11) M) and selectivity for Cys and GSH, and their fluorescence imaging of Cys and GSH in living cells was well demonstrated.
引用
收藏
页码：17672 / 17675
页数：4
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