Enteroviruses and Type 1 Diabetes Mellitus: An Overlooked Relationship in Some Regions

被引:14
|
作者
Alhazmi, Abdulaziz [1 ,2 ]
Sane, Famara [1 ]
Lazrek, Mouna [1 ]
Nekoua, Magloire Pandoua [1 ]
Badia-Boungou, Francis [1 ,3 ]
Engelmann, Ilka [1 ]
Alidjinou, Enagnon Kazali [1 ]
Hober, Didier [1 ]
机构
[1] Univ Lille, CHU Lille, Lab Virol, ULR3610, F-59000 Lille, France
[2] Jazan Univ, Dept Microbiol & Parasitol, Coll Med, Jazan 45142, Saudi Arabia
[3] Univ Abomey Calavi, Lab Biol & Physiol Cellulaires, Inst Sci Biomed Appl, Fac Sci & Tech FAST, 01 BP 526, Cotonou, Benin
关键词
enterovirus; type 1 diabetes mellitus; Middle East; North Africa; Asia; Cuba; DIFFERENT EUROPEAN POPULATIONS; BETA-CELL AUTOIMMUNITY; COXSACKIEVIRUS B1; RISING INCIDENCE; SAUDI-ARABIA; CORD BLOOD; CHILDREN; ANTIBODIES; EPIDEMIOLOGY; PATHOGENESIS;
D O I
10.3390/microorganisms8101458
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Enteroviruses (EVs) infect millions of people annually. EV infections can be asymptomatic or symptomatic with conditions ranging from mild illnesses to serious diseases such as dilated cardiomyopathy. A causal relationship between EV infections and type 1 diabetes mellitus (T1DM) has been heavily debated, with some studies suggesting that this relationship is not yet conclusive and requires additional evidence, whereas others strongly argue for this correlation. While this relationship is well investigated in some developed countries like the USA and Finland, it is understudied or neglected in other countries like Russia for many reasons such as the low incidence of T1DM. Although the Middle East and North Africa (MENA) are highly affected by T1DM, the role of EVs in the disease in MENA has not been investigated extensively. Therefore, we aimed to address the relationship between T1DM and EVs in MENA and other regions globally.
引用
收藏
页码:1 / 14
页数:14
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