The Brucella pathogens are polarized bacteria

被引:24
作者
Van der Henst, Charles [1 ]
de Barsy, Marie [2 ,3 ]
Zorreguieta, Angeles [4 ]
Letesson, Jean-Jacques [5 ]
De Bolle, Xavier [5 ]
机构
[1] Ecole Polytech Fed Lausanne, Sch Life Sci, Global Hlth Inst, CH-1015 Lausanne, Switzerland
[2] Univ Lausanne, Inst Microbiol, CH-1011 Lausanne, Switzerland
[3] Univ Hosp Ctr, CH-1011 Lausanne, Switzerland
[4] Fdn Inst Leloir, Buenos Aires, DF, Argentina
[5] Univ Namur, URBM, B-5000 Namur, Belgium
关键词
Polarity; Brucella; Growth; Adhesion; Cell cycle; Host-pathogen interaction; CELL-CYCLE PROGRESSION; ALPHA-PROTEOBACTERIA; ESCHERICHIA-COLI; CAULOBACTER; ABORTUS; 2-COMPONENT; PROTEIN; KINASE; SUIS; IDENTIFICATION;
D O I
10.1016/j.micinf.2013.10.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Brucella pathogens are responsible for brucellosis, a worldwide zoonosis. They are facultative intracellular pathogens characterized by their asymmetric division and their unipolar growth. This growth modality generates poles with specialized functions (through polar recruitment of polar adhesins or of cell cycle regulators) and progeny cells with potentially different fates. (C) 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:998 / 1004
页数:7
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