NRF2 as an Emerging Therapeutic Target

被引:39
作者
Copple, Ian M. [1 ]
Dinkova-Kostova, Albena T. [2 ]
Kensler, Thomas W. [3 ]
Liby, Karen T. [4 ]
Wigley, W. Christian [5 ]
机构
[1] Univ Liverpool, MRC Ctr Drug Safety Sci, Dept Mol & Clin Pharmacol, Liverpool L69 3GE, Merseyside, England
[2] Univ Dundee, Sch Med, Div Canc Res, Dundee DD1 9SY, Scotland
[3] Univ Pittsburgh, Dept Pharmacol & Chem Biol, Pittsburgh, PA 15261 USA
[4] Michigan State Univ, Dept Pharmacol & Toxicol, E Lansing, MI 48824 USA
[5] Reata Pharmaceut Inc, 2801 Gateway Dr, Irving, TX 75063 USA
关键词
D O I
10.1155/2017/8165458
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:2
相关论文
共 6 条
[1]   Effects of dimethyl fumarate on neuroprotection and immunomodulation [J].
Albrecht, Philipp ;
Bouchachia, Imane ;
Goebels, Norbert ;
Henke, Nadine ;
Hofstetter, Harald H. ;
Issberner, Andrea ;
Kovacs, Zsuzsa ;
Lewerenz, Jan ;
Lisak, Dmitrij ;
Maher, Pamela ;
Mausberg, Anne-Kathrin ;
Quasthoff, Kim ;
Zimmermann, Corinna ;
Hartung, Hans-Peter ;
Methner, Axel .
JOURNAL OF NEUROINFLAMMATION, 2012, 9
[2]  
Clarke Jessica L., 2016, Current Opinion in Toxicology, V1, P104, DOI 10.1016/j.cotox.2016.10.004
[3]   In vivo and invitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity [J].
Luchtman, Dirk ;
Gollan, Rene ;
Ellwardt, Erik ;
Birkenstock, Jerome ;
Robohm, Kerstin ;
Siffrin, Volker ;
Zipp, Frauke .
JOURNAL OF NEUROCHEMISTRY, 2016, 136 (05) :971-980
[4]   Toward clinical application of the Keap1-Nrf2 pathway [J].
Suzuki, Takafumi ;
Motohashi, Hozumi ;
Yamamoto, Masayuki .
TRENDS IN PHARMACOLOGICAL SCIENCES, 2013, 34 (06) :340-346
[5]   Peptide and small molecule inhibitors of the Keap1-Nrf2 protein-protein interaction [J].
Wells, Geoff .
BIOCHEMICAL SOCIETY TRANSACTIONS, 2015, 43 :674-679
[6]   Age-Related Retinopathy in NRF2-Deficient Mice [J].
Zhao, Zhenyang ;
Chen, Yan ;
Wang, Jian ;
Sternberg, Paul ;
Freeman, Michael L. ;
Grossniklaus, Hans E. ;
Cai, Jiyang .
PLOS ONE, 2011, 6 (04)