Genetics of alcohol withdrawal

被引：33
作者：
Schmidt, LG [1 ]
Sander, T [1 ]
机构：
[1] Free Univ Berlin, Dept Psychiat, D-14050 Berlin, Germany
来源：
EUROPEAN PSYCHIATRY | 2000年 / 15卷 / 02期
关键词：
alcoholism; dopamine; GABA; genes; genetics; opioids; serotonin; withdrawal;
D O I：
10.1016/S0924-9338(00)00220-0
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Alcohol withdrawal is a clinically and etiologically heterogeneous syndrome caused by a complex interaction of environmental (e.g., amount of ethanol) and genetic factors. Multiple genes are considered to be involved in various components of the syndrome, each of them contributing only modestly to withdrawal vulnerability. Association studies using candidate genes of the dopamine, serotonin, gabaergic and opioidergic systems are reviewed and methodological limitations are discussed. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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收藏
页码：135 / 139
页数：5
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