Cadmium, lead and endometriosis

被引：19
|
作者：
Heilier, J. F.
Donnez, J.
Verougstraete, V.
Donnez, O.
Grandjean, F.
Haufroid, V.
Nackers, F.
Lison, D.
机构：
[1] Catholic Univ Louvain, Fac Med, Ind Toxicol & Occupat Med Unit, B-1200 Brussels, Belgium
[2] Clin Univ St Luc, Dept Gynaecol, B-1200 Brussels, Belgium
[3] Catholic Univ Louvain, Gyneacol Unit, B-1348 Louvain, Belgium
[4] Catholic Univ Louvain, Epidemiol Biostat & Operat Methods Unit, B-1348 Louvain, Belgium
来源：
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 2006年 / 80卷 / 02期
关键词：
cadmium; lead; endometriosis; deep endometriotic nodules; endocrine disruptors;
D O I：
10.1007/s00420-006-0114-7
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objectives: Cadmium (Cd) and lead (Pb) have been demonstrated to exert endocrine disrupting activities. Their possible role in endometriosis, an oestrogen-dependent disease, is unknown. Methods: We compared cadmium urinary excretion (CdU) and blood concentration of cadmium (CdB) and lead (PbB) in 119 patients with peritoneal endometriosis and/or deep endometriotic (adenomyotic) nodules of the rectovaginal septum and 25 controls. Results: The mean levels of cadmium in urine and blood did not differ among the groups. Women suffering from endometriotic diseases showed lower levels of PbB than controls. Conclusions: These data do not support a role for cadmium in the onset or the growth of endometriotic diseases but suggest a possible relationship with lead.
引用
收藏
页码：149 / 153
页数：5
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