Cadmium, lead and endometriosis

被引：19

作者：

Heilier, J. F.

Donnez, J.

Verougstraete, V.

Donnez, O.

Grandjean, F.

Haufroid, V.

Nackers, F.

Lison, D.

机构：

[1] Catholic Univ Louvain, Fac Med, Ind Toxicol & Occupat Med Unit, B-1200 Brussels, Belgium

[2] Clin Univ St Luc, Dept Gynaecol, B-1200 Brussels, Belgium

[3] Catholic Univ Louvain, Gyneacol Unit, B-1348 Louvain, Belgium

[4] Catholic Univ Louvain, Epidemiol Biostat & Operat Methods Unit, B-1348 Louvain, Belgium

来源：

INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 2006年 / 80卷 / 02期

关键词：

cadmium; lead; endometriosis; deep endometriotic nodules; endocrine disruptors;

D O I：

10.1007/s00420-006-0114-7

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objectives: Cadmium (Cd) and lead (Pb) have been demonstrated to exert endocrine disrupting activities. Their possible role in endometriosis, an oestrogen-dependent disease, is unknown. Methods: We compared cadmium urinary excretion (CdU) and blood concentration of cadmium (CdB) and lead (PbB) in 119 patients with peritoneal endometriosis and/or deep endometriotic (adenomyotic) nodules of the rectovaginal septum and 25 controls. Results: The mean levels of cadmium in urine and blood did not differ among the groups. Women suffering from endometriotic diseases showed lower levels of PbB than controls. Conclusions: These data do not support a role for cadmium in the onset or the growth of endometriotic diseases but suggest a possible relationship with lead.

引用

页码：149 / 153

页数：5

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