A Growing Population of Older Adults with Sickle Cell Disease

被引：8

作者：

Shet, Arun S. ^{[1
]}

Thein, Swee Lay ^{[1
]}

机构：

[1] NHLBI, Sickle Cell Branch, NIH, Bldg 10 CRC,10 Ctr Dr, Bethesda, MD 20892 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2019年 / 35卷 / 03期

关键词：

Sickle cell disease; Aging- and disease-related morbidities; Disease-modifying therapies; Curative therapies; ACUTE CHEST SYNDROME; HEMOLYTIC TRANSFUSION REACTION; PULMONARY-HYPERTENSION; NATURAL-HISTORY; HEMOGLOBIN SS; IRON OVERLOAD; GENE-THERAPY; RISK-FACTORS; MANAGEMENT; CHILDREN;

D O I：

10.1016/j.cger.2019.03.006

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

In countries with organized access to health care, survival of patients with sickle cell disease (SCD) has greatly improved, shifting the burden of care from a pediatrician to an internal medicine physician. As a consequence, cumulative disease complications related to chronic vasculopathy are becoming more apparent, adding to organ dysfunction from physiologic aging. The time has come for us to reevaluate the approach to managing the older adult with SCD by putting a greater emphasis on geriatric conditions while proactively considering curative options once previously offered only to younger patients, with comprehensive annual assessments and joint clinics with relevant specialists.

引用

页码：349 / +

页数：20

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