A facile and convenient synthesis of 1H-isoindole-1,3(2H)-diones

被引：11

作者：

Nikpour, Farzad ^{[1
]}

Kazemi, Samira ^{[1
]}

Sheikh, Davood ^{[1
]}

机构：

[1] Univ Kurdistan, Fac Sci, Dept Chem, Sanandaj, Iran

来源：

HETEROCYCLES | 2006年 / 68卷 / 08期

关键词：

phthalimide; 1H-isoindole-1,3(2H)-dione; microwave irradiation; potassium cyanate; sodium thiocyanate;

D O I：

10.3987/COM-06-10762

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of 1H-isoindole-1,3(2H)-diones (3a-h) has been developed by the reaction of the corresponding anhydrides (la-h) with potassium cyanate (4a) or sodium thiocyanate (4b). The reactions were carried out in neutral media under reflux or under microwave irradiation without use of catalyst. Good to excellent yields of the products were obtained in high purity with very simple work-up.

引用

页码：1559 / 1564

页数：6

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