Effects of Long-term Regular Exercise on Cognitive Function, Lipid Profile and Atherogenic Biomarkers in Middle-aged Men

被引:0
作者
Klapcinska, Barbara [1 ]
Kroemeke, Aleksandra [2 ]
Tataruch, Magdalena [3 ]
Tataruch, Rafat [3 ]
Szoltysek-Boldys, Izabela [4 ]
Derejczyk, Jaroslaw [2 ]
Kimsa, Elzbieta
Iskra, Janusz [3 ]
机构
[1] Acad Phys Educ Katowice, Dept Biochem, PL-40065 Katowice, Poland
[2] Geriatr Hosp Katowice, Katowice, Poland
[3] Opole Univ Technol, Fac Phys Educ & Physiotherapy, Opole, Poland
[4] Med Univ Silesia, Sch Pharm, Sosnowiec, Poland
关键词
cognitive function; lipid profile; physical exercise;
D O I
暂无
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Several studies on exercise and its effect on cognitive function in human and animal populations have documented the beneficial impact Of regular physical activity on maintenance of good cognitive abilities and satisfactory health-related qualify well into older age. The aim of the study was to evaluate the effects of long-tern? regular running on metabolic profile and cognitive function in middle-aged men. A total of 24 regularly exercising, middle-age men (Group A), all being members of the Runners Club, and 22 age-matched sedentary subjects (Group B), as the control group, were enrolled it? this study. The control group included 8 non-overwight (BMI=23.5 +/- 5.2) individuals (Group Q and 14 overweight/obese (BMI=30.7 +/- 1.6) subjects (Group D). Serum lipid profile, glucose and homocysteine concentrations were assessed by routine laboratory methods. Subjects' cognitive function was evaluated based on Trail Making Test (TMT) and Digit Symbol Test (DST) scores. In a majority of runners (Group A), the BMI and the parameters of lipid profile (TC, HDL, LDL, TG, glycerol) were close to those recorded in non-overweight controsl (Group C) and, in both groups, results were ideally within the reference ranges for healthy male subjects. However, as compared to the whole control group (Group B), which may be considered as an average population sample of sedentary middle-age men, significant differences were observed in BMI and concentrations of TC and LDL, as well as in the pro-atherogenic biomarkers (TC/HDL, LDL/HDL), which were lower in runners. A similar tendency was found in concentrations of TG (independent cardiovascular risk factor), glycerol and TG/HDL ratio (surrogate measure of insulin resistance), however the differences did not reach the level of significance. The level of homocysteine (pro-atherogenic biomarker) was comparable in all groups, and in most cases, within the reference range for male adults. Results of cognitive function tests did not reveal any significant between-group differences. The TMT score was found to be correlated positivel (r=0,492, p < 0.05), whereas DST score was correlated negatively (r=0.549, p < 0.005), with age. The DST performance, as evaluated in the group of runners (Group A), appeared to be strongly dependent (r=0.809,p < 0.005)on the educational level of the subject. These data provided evidence of beneficial effects of a long-term regular endurance running exercise on lipid profile and cardiovascular health in middle-aged men. However, we failed to confirm the findings of a favorable impact of regular physical activity on improvement in cognitive abilities.
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页码:89 / 98
页数:10
相关论文
共 45 条
  • [1] Low physical activity as a predictor for total and cardiovascular disease mortality in middle-aged men and women in Finland
    Barengo, NC
    Hu, G
    Lakka, TA
    Pekkarinen, H
    Nissinen, A
    Tuomilehto, J
    [J]. EUROPEAN HEART JOURNAL, 2004, 25 (24) : 2204 - 2211
  • [2] A METAANALYSIS OF PHYSICAL-ACTIVITY IN THE PREVENTION OF CORONARY HEART-DISEASE
    BERLIN, JA
    COLDITZ, GA
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1990, 132 (04) : 612 - 628
  • [3] Blair SN, 2004, AM J CLIN NUTR, V79, P913
  • [4] BRZEZIRISKI J, 2004, INTELIGENCJI WECHSLE
  • [5] Buege J A, 1978, Methods Enzymol, V52, P302
  • [6] Exercise Increases the Plasma Antioxidant Capacity of Adolescent Athletes
    Carlsohn, Anja
    Rohn, Sascha
    Bittmann, Frank
    Raila, Jens
    Mayer, Frank
    Schweigert, Florian J.
    [J]. ANNALS OF NUTRITION AND METABOLISM, 2008, 53 (02) : 96 - 103
  • [7] Reduced disability and mortality among aging runners - A 21-year longitudinal study
    Chakravarty, Eliza F.
    Hubert, Helen B.
    Lingala, Vijaya B.
    Fries, James F.
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (15) : 1638 - 1646
  • [8] Exercise enhances and protects brain function
    Cotman, CW
    Engesser-Cesar, C
    [J]. EXERCISE AND SPORT SCIENCES REVIEWS, 2002, 30 (02): : 75 - 79
  • [9] Evidence that triglycerides are an independent coronary heart disease risk factor
    Cullen, P
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2000, 86 (09) : 943 - 949
  • [10] Ergun M, 2006, J SPORT SCI MED, V5, P266