The Cell Cycle Ontology: an application ontology for the representation and integrated analysis of the cell cycle process

被引:29
作者
Antezana, Erick [2 ,3 ]
Egana, Mikel [4 ]
Blonde, Ward [5 ]
Illarramendi, Aitzol [6 ]
Bilbao, Inaki [6 ]
De Baets, Bernard [5 ]
Stevens, Robert [4 ]
Mironov, Vladimir [1 ]
Kuiper, Martin [1 ]
机构
[1] Norwegian Univ Sci & Technol, Dept Biol, NO-7491 Trondheim, Norway
[2] Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium
[3] Univ Ghent, Dept Mol Genet, B-9052 Ghent, Belgium
[4] Univ Manchester, Sch Comp Sci, Manchester M13 9PL, Lancs, England
[5] Univ Ghent, Dept Appl Math Biometr & Comp Sci, B-9000 Ghent, Belgium
[6] Noray Bioinformat, Derio 48160, Bizkaia, Spain
基金
英国工程与自然科学研究理事会;
关键词
SEMANTIC WEB TECHNOLOGIES; GENE-ONTOLOGY; SYSTEMS BIOLOGY; BIOMEDICAL ONTOLOGIES; BIO-ONTOLOGIES; DATABASE; OBO; ORGANIZATION; EVOLUTION; DESIGN;
D O I
10.1186/gb-2009-10-5-r58
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The Cell Cycle Ontology (http://www.CellCycleOntology.org) is an application ontology that automatically captures and integrates detailed knowledge on the cell cycle process. Cell Cycle Ontology is enabled by semantic web technologies, and is accessible via the web for browsing, visualizing, advanced querying, and computational reasoning. Cell Cycle Ontology facilitates a detailed analysis of cell cycle-related molecular network components. Through querying and automated reasoning, it may provide new hypotheses to help steer a systems biology approach to biological network building.
引用
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页数:20
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